Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH)
Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are fast becoming the most common chronic liver disease and are often preventable with healthy dietary habits and weight management. Sugar-sweetened beverage (SSB) consumption is associated with obesity and NAFLD. Howev...
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| Format: | Article |
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MDPI AG
2023-09-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/18/3997 |
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| author | Tung-Sung Tseng Wei-Ting Lin Peng-Sheng Ting Chiung-Kuei Huang Po-Hung Chen Gabrielle V. Gonzalez Hui-Yi Lin |
| author_facet | Tung-Sung Tseng Wei-Ting Lin Peng-Sheng Ting Chiung-Kuei Huang Po-Hung Chen Gabrielle V. Gonzalez Hui-Yi Lin |
| author_sort | Tung-Sung Tseng |
| collection | DOAJ |
| description | Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are fast becoming the most common chronic liver disease and are often preventable with healthy dietary habits and weight management. Sugar-sweetened beverage (SSB) consumption is associated with obesity and NAFLD. However, the impact of different types of SSBs, including artificially sweetened beverages (ASBs), is not clear after controlling for total sugar intake and total caloric intake. The aim of this study was to examine the association between the consumption of different SSBs and the risk of NAFLD and NASH in US adults. The representativeness of 3739 US adults aged ≥20 years old who had completed 24 h dietary recall interviews and measurements, including dietary, SSBs, smoking, physical activity, and liver stiffness measurements, were selected from the National Health and Nutrition Examination Survey 2017–2020 surveys. Chi-square tests, t-tests, and weighted logistic regression models were utilized for analyses. The prevalence of NASH was 20.5%, and that of NAFLD (defined without NASH) was 32.7% of US. adults. We observed a higher prevalence of NASH/NAFLD in men, Mexican-Americans, individuals with sugar intake from SSBs, light–moderate alcohol use, lower physical activity levels, higher energy intake, obesity, and medical comorbidities. Heavy sugar consumption through SSBs was significantly associated with NAFLD (aOR = 1.60, 95% CI = 1.05–2.45). In addition, the intake of ASBs only (compared to the non-SSB category) was significantly associated with NAFLD (aOR = 1.78, 95% CI = 1.04–3.05), after adjusting for demographic, risk behaviors, and body mass index. A higher sugar intake from SSBs and exclusive ASB intake are both associated with the risk of NAFLD. |
| first_indexed | 2024-03-10T22:20:19Z |
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| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T22:20:19Z |
| publishDate | 2023-09-01 |
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| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-5976af0dde394dcab3c075dde5851dc72023-11-19T12:18:54ZengMDPI AGNutrients2072-66432023-09-011518399710.3390/nu15183997Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH)Tung-Sung Tseng0Wei-Ting Lin1Peng-Sheng Ting2Chiung-Kuei Huang3Po-Hung Chen4Gabrielle V. Gonzalez5Hui-Yi Lin6Behavior and Community Health Sciences Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USASocial, Behavioral, and Population Sciences, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, New Orleans, LA 70112, USADivision of Gastroenterology and Hepatology, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USADivision of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, 1830 East Monument Street, 4th Floor, Baltimore, MD 21287, USABehavior and Community Health Sciences Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USABiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USANonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are fast becoming the most common chronic liver disease and are often preventable with healthy dietary habits and weight management. Sugar-sweetened beverage (SSB) consumption is associated with obesity and NAFLD. However, the impact of different types of SSBs, including artificially sweetened beverages (ASBs), is not clear after controlling for total sugar intake and total caloric intake. The aim of this study was to examine the association between the consumption of different SSBs and the risk of NAFLD and NASH in US adults. The representativeness of 3739 US adults aged ≥20 years old who had completed 24 h dietary recall interviews and measurements, including dietary, SSBs, smoking, physical activity, and liver stiffness measurements, were selected from the National Health and Nutrition Examination Survey 2017–2020 surveys. Chi-square tests, t-tests, and weighted logistic regression models were utilized for analyses. The prevalence of NASH was 20.5%, and that of NAFLD (defined without NASH) was 32.7% of US. adults. We observed a higher prevalence of NASH/NAFLD in men, Mexican-Americans, individuals with sugar intake from SSBs, light–moderate alcohol use, lower physical activity levels, higher energy intake, obesity, and medical comorbidities. Heavy sugar consumption through SSBs was significantly associated with NAFLD (aOR = 1.60, 95% CI = 1.05–2.45). In addition, the intake of ASBs only (compared to the non-SSB category) was significantly associated with NAFLD (aOR = 1.78, 95% CI = 1.04–3.05), after adjusting for demographic, risk behaviors, and body mass index. A higher sugar intake from SSBs and exclusive ASB intake are both associated with the risk of NAFLD.https://www.mdpi.com/2072-6643/15/18/3997sugar-sweetened beverage (SSBs)artificially sweetened beverages (ASBs)nonalcoholic fatty liver disease (NAFLD)nonalcoholic steatohepatitis (NASH)NHANES |
| spellingShingle | Tung-Sung Tseng Wei-Ting Lin Peng-Sheng Ting Chiung-Kuei Huang Po-Hung Chen Gabrielle V. Gonzalez Hui-Yi Lin Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH) Nutrients sugar-sweetened beverage (SSBs) artificially sweetened beverages (ASBs) nonalcoholic fatty liver disease (NAFLD) nonalcoholic steatohepatitis (NASH) NHANES |
| title | Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH) |
| title_full | Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH) |
| title_fullStr | Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH) |
| title_full_unstemmed | Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH) |
| title_short | Sugar-Sweetened Beverages and Artificially Sweetened Beverages Consumption and the Risk of Nonalcoholic Fatty Liver (NAFLD) and Nonalcoholic Steatohepatitis (NASH) |
| title_sort | sugar sweetened beverages and artificially sweetened beverages consumption and the risk of nonalcoholic fatty liver nafld and nonalcoholic steatohepatitis nash |
| topic | sugar-sweetened beverage (SSBs) artificially sweetened beverages (ASBs) nonalcoholic fatty liver disease (NAFLD) nonalcoholic steatohepatitis (NASH) NHANES |
| url | https://www.mdpi.com/2072-6643/15/18/3997 |
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