Reference values for spirometric variables for allegedly healthy workers
Introduction: Spirometry in workers exposed to air pollutants allows for early identification of lung function impairment. Reference values (RV) for spirometric variables (SV) obtained in Cuban workers (CW) are not available. Objective: To obtain adequate SV-specific RV adequate for supposedly healt...
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| Format: | Article |
| Language: | English |
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Universidad Nacional de Colombia
2018-04-01
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| Series: | Revista de la Facultad de Medicina |
| Subjects: | |
| Online Access: | https://revistas.unal.edu.co/index.php/revfacmed/article/view/63571 |
| _version_ | 1819266280542175232 |
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| author | Sergio Santana-Porbén Adamara González-Marrero Juan Pablo Valdivieso-Valdivieso Santiago Álvarez-Porbén |
| author_facet | Sergio Santana-Porbén Adamara González-Marrero Juan Pablo Valdivieso-Valdivieso Santiago Álvarez-Porbén |
| author_sort | Sergio Santana-Porbén |
| collection | DOAJ |
| description | Introduction: Spirometry in workers exposed to air pollutants allows for early identification of lung function impairment. Reference values (RV) for spirometric variables (SV) obtained in Cuban workers (CW) are not available.
Objective: To obtain adequate SV-specific RV adequate for supposedly healthy CW.
Materials and methods: Retrospective, analytical study. Forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC ratio and 25-75% forced expiration fraction for FVC (FEF25-75) values were observed in 1 088 allegedly healthy, non-smoker workers from both sexes, aged between 20 - 65 years, assisted at the Instituto Nacional de la Salud de los Trabajadores (INSAT) in Havana (Cuba) between 2009 and 2015. RV were obtained for each sex as solutions of the regression function (RF) Y=α+β x age+χ x height+ε (Y: FVC, FSV1, FEV1/FVC, FEF25-75).
Results: Advanced ages were associated with lower FVC and FEV1. Taller individuals showed higher FVC and FEV1. A RF including age and height implied a higher coefficient of determination r2 and lower estimation of ε error. Behavior of SV values predicted with the locally developed equation was less biased than those obtained with other foreign equations.
Conclusions: Locally developed RV may be more effective for diagnosing lung diseases in CW. |
| first_indexed | 2024-12-23T20:58:46Z |
| format | Article |
| id | doaj.art-597a73a457864ef1ac144870e2ad5aec |
| institution | Directory Open Access Journal |
| issn | 0120-0011 2357-3848 |
| language | English |
| last_indexed | 2024-12-23T20:58:46Z |
| publishDate | 2018-04-01 |
| publisher | Universidad Nacional de Colombia |
| record_format | Article |
| series | Revista de la Facultad de Medicina |
| spelling | doaj.art-597a73a457864ef1ac144870e2ad5aec2022-12-21T17:31:25ZengUniversidad Nacional de ColombiaRevista de la Facultad de Medicina0120-00112357-38482018-04-0166217918510.15446/revfacmed.v66n2.6357148525Reference values for spirometric variables for allegedly healthy workersSergio Santana-Porbén0Adamara González-Marrero1Juan Pablo Valdivieso-Valdivieso2Santiago Álvarez-Porbén3Instituto Nacional de Salud de los Trabajadores - Deputy Director’s Office for Investigations - Havana - Cuba.Instituto Nacional de Salud de los Trabajadores - Deputy Director’s Office of Nursing - Havana - Cuba.Instituto Nacional de Salud de los Trabajadores - Deputy Director’s Office for Investigations - Havana - Cuba.Hospital Pediátrico Docente Juan Manuel Márquez - Clinical Laboratory Service - Havana - Cuba.Introduction: Spirometry in workers exposed to air pollutants allows for early identification of lung function impairment. Reference values (RV) for spirometric variables (SV) obtained in Cuban workers (CW) are not available. Objective: To obtain adequate SV-specific RV adequate for supposedly healthy CW. Materials and methods: Retrospective, analytical study. Forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC ratio and 25-75% forced expiration fraction for FVC (FEF25-75) values were observed in 1 088 allegedly healthy, non-smoker workers from both sexes, aged between 20 - 65 years, assisted at the Instituto Nacional de la Salud de los Trabajadores (INSAT) in Havana (Cuba) between 2009 and 2015. RV were obtained for each sex as solutions of the regression function (RF) Y=α+β x age+χ x height+ε (Y: FVC, FSV1, FEV1/FVC, FEF25-75). Results: Advanced ages were associated with lower FVC and FEV1. Taller individuals showed higher FVC and FEV1. A RF including age and height implied a higher coefficient of determination r2 and lower estimation of ε error. Behavior of SV values predicted with the locally developed equation was less biased than those obtained with other foreign equations. Conclusions: Locally developed RV may be more effective for diagnosing lung diseases in CW.https://revistas.unal.edu.co/index.php/revfacmed/article/view/63571SpirometryReference ValuesOccupational Health |
| spellingShingle | Sergio Santana-Porbén Adamara González-Marrero Juan Pablo Valdivieso-Valdivieso Santiago Álvarez-Porbén Reference values for spirometric variables for allegedly healthy workers Revista de la Facultad de Medicina Spirometry Reference Values Occupational Health |
| title | Reference values for spirometric variables for allegedly healthy workers |
| title_full | Reference values for spirometric variables for allegedly healthy workers |
| title_fullStr | Reference values for spirometric variables for allegedly healthy workers |
| title_full_unstemmed | Reference values for spirometric variables for allegedly healthy workers |
| title_short | Reference values for spirometric variables for allegedly healthy workers |
| title_sort | reference values for spirometric variables for allegedly healthy workers |
| topic | Spirometry Reference Values Occupational Health |
| url | https://revistas.unal.edu.co/index.php/revfacmed/article/view/63571 |
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