Mismatch oligonucleotides in human and yeast: guidelines for probe design on tiling microarrays

Mismatch oligonucleotides in human and yeast: guidelines for probe design on tiling microarrays

<p>Abstract</p> <p>Background</p> <p>Mismatched oligonucleotides are widely used on microarrays to differentiate specific from nonspecific hybridization. While many experiments rely on such oligos, the hybridization behavior of various degrees of mismatch (MM) structure...

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Bibliographic Details
Main Authors: Jee Justin, Nagalakshmi Ugrappa, Royce Thomas, Rozowsky Joel, Seringhaus Michael, Snyder Michael, Gerstein Mark
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/635

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