Cerebellar spreading depolarization mediates paroxysmal movement disorder

Cerebellar spreading depolarization mediates paroxysmal movement disorder

Summary: Paroxysmal kinesigenic dyskinesia (PKD) is the most common paroxysmal dyskinesia, characterized by recurrent episodes of involuntary movements provoked by sudden changes in movement. Proline-rich transmembrane protein 2 (PRRT2) has been identified as the major causative gene for PKD. Here,...

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Bibliographic Details
Main Authors: Bin Lu, Sen-Sen Lou, Ruo-Shui Xu, De-Lun Kong, Rong-Jie Wu, Jing Zhang, Ling Zhuang, Xue-Mei Wu, Jun-Yan He, Zhi-Ying Wu, Zhi-Qi Xiong
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
spreading depolarization
PRRT2
Nav channel
inactivation
cerebellum
cerebellar granule cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721011967

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