Incidence of lung cancer and mortality among civil construction industry workers: A protocol for a systematic review and meta-analysis.

<h4>Background</h4>The construction sector is one of the most stable growth industries in the world. However, many studies have suggested an association between occupational exposure in civil construction and lung cancer risk. Thus, this study aims to assess lung cancer risk in civil con...

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Main Authors: Rita Stella Maria Cahuana Pinto, Alana Castro Panzenhagen, Luis Felipe Silva Oliveira, José Claudio Fonseca Moreira, Carlos Eduardo Schnorr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0250377
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author Rita Stella Maria Cahuana Pinto
Alana Castro Panzenhagen
Luis Felipe Silva Oliveira
José Claudio Fonseca Moreira
Carlos Eduardo Schnorr
author_facet Rita Stella Maria Cahuana Pinto
Alana Castro Panzenhagen
Luis Felipe Silva Oliveira
José Claudio Fonseca Moreira
Carlos Eduardo Schnorr
author_sort Rita Stella Maria Cahuana Pinto
collection DOAJ
description <h4>Background</h4>The construction sector is one of the most stable growth industries in the world. However, many studies have suggested an association between occupational exposure in civil construction and lung cancer risk. Thus, this study aims to assess lung cancer risk in civil construction workers occupationally exposed to physical and chemical agents through a systematic review and meta-analysis.<h4>Methods/design</h4>Studies will be identified by searching PUBMED, Embase, SCOPUS, WEB OF SCIENCE and the reference list of included articles. Eligible study designs will be cohort, cross-sectional, and case-control studies that report occupational exposure to physical or chemical agents and lung cancer risk through mortality or incidence outcomes. A meta-analysis will be used to combine odds ratios (ORs) from case-control studies and relative risks (RR) from cohort studies. Two reviewers will independently screen articles, extract data, and assess scientific quality using standardized forms and ROBINS-E tool if available. Otherwise, the New-Castle Ottawa rating scale will be used. Any of those will also be used in combination with the GRADE approach for quality of evidence. Overall risk estimates and their corresponding 95% confidence intervals (CIs) will be obtained using the random-effects model meta-analysis. This systematic review and meta-analysis will be conducted following the Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines. Results will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.<h4>Discussion</h4>This review will identify and synthesize studies investigating the association between occupational exposure in the construction industry and lung cancer. The findings will help governmental entities and researchers with evidence-based decision-making because they will integrate and validate the evidence on construction workers' health effects due to occupational exposure.<h4>Systematic review registration</h4>PROSPERO CRD42020164209.
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spelling doaj.art-598177600674481882da75624d40a3382022-12-21T19:09:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01164e025037710.1371/journal.pone.0250377Incidence of lung cancer and mortality among civil construction industry workers: A protocol for a systematic review and meta-analysis.Rita Stella Maria Cahuana PintoAlana Castro PanzenhagenLuis Felipe Silva OliveiraJosé Claudio Fonseca MoreiraCarlos Eduardo Schnorr<h4>Background</h4>The construction sector is one of the most stable growth industries in the world. However, many studies have suggested an association between occupational exposure in civil construction and lung cancer risk. Thus, this study aims to assess lung cancer risk in civil construction workers occupationally exposed to physical and chemical agents through a systematic review and meta-analysis.<h4>Methods/design</h4>Studies will be identified by searching PUBMED, Embase, SCOPUS, WEB OF SCIENCE and the reference list of included articles. Eligible study designs will be cohort, cross-sectional, and case-control studies that report occupational exposure to physical or chemical agents and lung cancer risk through mortality or incidence outcomes. A meta-analysis will be used to combine odds ratios (ORs) from case-control studies and relative risks (RR) from cohort studies. Two reviewers will independently screen articles, extract data, and assess scientific quality using standardized forms and ROBINS-E tool if available. Otherwise, the New-Castle Ottawa rating scale will be used. Any of those will also be used in combination with the GRADE approach for quality of evidence. Overall risk estimates and their corresponding 95% confidence intervals (CIs) will be obtained using the random-effects model meta-analysis. This systematic review and meta-analysis will be conducted following the Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines. Results will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.<h4>Discussion</h4>This review will identify and synthesize studies investigating the association between occupational exposure in the construction industry and lung cancer. The findings will help governmental entities and researchers with evidence-based decision-making because they will integrate and validate the evidence on construction workers' health effects due to occupational exposure.<h4>Systematic review registration</h4>PROSPERO CRD42020164209.https://doi.org/10.1371/journal.pone.0250377
spellingShingle Rita Stella Maria Cahuana Pinto
Alana Castro Panzenhagen
Luis Felipe Silva Oliveira
José Claudio Fonseca Moreira
Carlos Eduardo Schnorr
Incidence of lung cancer and mortality among civil construction industry workers: A protocol for a systematic review and meta-analysis.
PLoS ONE
title Incidence of lung cancer and mortality among civil construction industry workers: A protocol for a systematic review and meta-analysis.
title_full Incidence of lung cancer and mortality among civil construction industry workers: A protocol for a systematic review and meta-analysis.
title_fullStr Incidence of lung cancer and mortality among civil construction industry workers: A protocol for a systematic review and meta-analysis.
title_full_unstemmed Incidence of lung cancer and mortality among civil construction industry workers: A protocol for a systematic review and meta-analysis.
title_short Incidence of lung cancer and mortality among civil construction industry workers: A protocol for a systematic review and meta-analysis.
title_sort incidence of lung cancer and mortality among civil construction industry workers a protocol for a systematic review and meta analysis
url https://doi.org/10.1371/journal.pone.0250377
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