HPLC DETECTION OF ANTITHROMBITIC CALIX[4]ARENE IN BLOOD PLASMA OF ANIMALS

HPLC DETECTION OF ANTITHROMBITIC CALIX[4]ARENE IN BLOOD PLASMA OF ANIMALS

Previously sodium salt of 5,11,17,23-bis (dihydroxyphosphoryl) methylcalix[4]arene (C-145) was shown to be promising antithrombotic agent. Aim. This work was focused on the development of the method for the direct detection of this substance in blood plasma and estimation of pharmacokinetics of t...

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Bibliographic Details
Main Authors:	V. A. Didkivskyi, A. O. Pavlenko, R. Y.Marunych, A. O. Selikhova, S. O Cherenok, T. P. Todosiuk, S. M. Shevchenko
Format:	Article
Language:	English
Published:	National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2022-04-01
Series:	Biotechnologia Acta
Subjects:	calix[4]arene blood plasma thrombosis fibrinogen hplc.
Online Access:	http://biotechnology.kiev.ua/images/2_2022/didkivskyi_2_2022.pdf

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