Comparative analysis of the cardiomyocyte differentiation potential of induced pluripotent stem cells reprogrammed from human atrial or ventricular fibroblasts

Comparative analysis of the cardiomyocyte differentiation potential of induced pluripotent stem cells reprogrammed from human atrial or ventricular fibroblasts

Background: We had shown that cardiomyocytes (CMs) were more efficiently differentiated from human induced pluripotent stem cells (hiPSCs) when the hiPSCs were reprogrammed from cardiac fibroblasts rather than dermal fibroblasts or blood mononuclear cells. Here, we continued to investigate the relat...

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Bibliographic Details
Main Authors: Lu Wang, Thanh Nguyen, Manuel Rosa-Garrido, Yang Zhou, David C. Cleveland, Jianyi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
induced pluripotent stem cells
cardiac differentiation
action potential
field potential
calcium transient
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1108340/full

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