The identification and functional implications of human-specific "fixed" amino acid substitutions in the glutamate receptor family

The identification and functional implications of human-specific "fixed" amino acid substitutions in the glutamate receptor family

<p>Abstract</p> <p>Background</p> <p>The glutamate receptors (GluRs) play a vital role in the mediation of excitatory synaptic transmission in the central nervous system. To clarify the evolutionary dynamics and mechanisms of the GluR genes in the lineage leading to hum...

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Main Authors: Fujiyama Asao, Sakaki Yoshiyuki, Hattori Masahira, Toyoda Atsushi, Kuroki Yoko, Tanaka Kunika, Kageyama Rui, Araragi Naozumi, Watanabe Kazunori, Goto Hiroki, Fukumaki Yasuyuki, Shibata Hiroki
Format: Article
Language:English
Published: BMC 2009-09-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/9/224

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http://www.biomedcentral.com/1471-2148/9/224

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