STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing
The cytoplasm in mammalian cells is considered homogeneous. Here authors report that the cytoplasmic fluidity is regulated in the blebbing cells, which is regulated by calcium concentration in the expanding blebs and involves the STIM-Orai1 pathway.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-20826-5 |
| _version_ | 1818428947781648384 |
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| author | Kana Aoki Shota Harada Keita Kawaji Kenji Matsuzawa Seiichi Uchida Junichi Ikenouchi |
| author_facet | Kana Aoki Shota Harada Keita Kawaji Kenji Matsuzawa Seiichi Uchida Junichi Ikenouchi |
| author_sort | Kana Aoki |
| collection | DOAJ |
| description | The cytoplasm in mammalian cells is considered homogeneous. Here authors report that the cytoplasmic fluidity is regulated in the blebbing cells, which is regulated by calcium concentration in the expanding blebs and involves the STIM-Orai1 pathway. |
| first_indexed | 2024-12-14T15:09:43Z |
| format | Article |
| id | doaj.art-598b58b973cd48b894dc8e2963314ae4 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T15:09:43Z |
| publishDate | 2021-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-598b58b973cd48b894dc8e2963314ae42022-12-21T22:56:36ZengNature PortfolioNature Communications2041-17232021-01-0112111310.1038/s41467-020-20826-5STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbingKana Aoki0Shota Harada1Keita Kawaji2Kenji Matsuzawa3Seiichi Uchida4Junichi Ikenouchi5Department of Biology, Faculty of Sciences, Kyushu UniversityDepartment of Advanced Information Technology, Kyushu UniversityDepartment of Advanced Information Technology, Kyushu UniversityDepartment of Biology, Faculty of Sciences, Kyushu UniversityDepartment of Advanced Information Technology, Kyushu UniversityDepartment of Biology, Faculty of Sciences, Kyushu UniversityThe cytoplasm in mammalian cells is considered homogeneous. Here authors report that the cytoplasmic fluidity is regulated in the blebbing cells, which is regulated by calcium concentration in the expanding blebs and involves the STIM-Orai1 pathway.https://doi.org/10.1038/s41467-020-20826-5 |
| spellingShingle | Kana Aoki Shota Harada Keita Kawaji Kenji Matsuzawa Seiichi Uchida Junichi Ikenouchi STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing Nature Communications |
| title | STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing |
| title_full | STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing |
| title_fullStr | STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing |
| title_full_unstemmed | STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing |
| title_short | STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing |
| title_sort | stim orai1 signaling regulates fluidity of cytoplasm during membrane blebbing |
| url | https://doi.org/10.1038/s41467-020-20826-5 |
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