The Impact of Corticosteroids on Human Airway Smooth Muscle Contractility and Airway Hyperresponsiveness: A Systematic Review

The Impact of Corticosteroids on Human Airway Smooth Muscle Contractility and Airway Hyperresponsiveness: A Systematic Review

Classically, the effects elicited by corticosteroids (CS) are mediated by the binding and activation of cytosolic glucocorticoid receptors (GR). However, several of the non-genomic effects of CS seem to be mediated by putative non-classic membrane receptors characterized by pharmacological propertie...

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Bibliographic Details
Main Authors: Luigino Calzetta, Alfredo Chetta, Marina Aiello, Elena Pistocchini, Paola Rogliani
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
AHR
airway smooth muscle
asthma
corticosteroid
genomic
non-genomic
Online Access:https://www.mdpi.com/1422-0067/23/23/15285

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