Effects of soluble β-amyloid on the release of neurotransmitters from rat brain synaptosomes.

Effects of soluble β-amyloid on the release of neurotransmitters from rat brain synaptosomes.

Contradictory results have been reported on the interaction of beta-amyloid (Aβ) with cholinergic receptors. The present paper investigates the modulatory effect of Aβ1-40 on the neurotransmitter release evoked by nicotinic (nAChRs) and muscarinic (mAChRs) receptors. Aβ1-40 inhibits both nicotinic a...

Full description

Bibliographic Details
Main Authors: Guendalina eOlivero, Massimo eGrilli, Jiayang eChen, Stefania ePreda, Elisa eMura, Stefano eGovoni, Mario eMarchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
nicotinic receptors
Alzheimer’s disease
beta amyloid
muscarinic receptors
Dopamine release
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00166/full

Similar Items

Similar Items