The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease
Abstract Multiple myeloma bone disease is characterized by the development of osteolytic bone lesions. Recent work identified matrix metalloproteinase 13 as a myeloma-derived fusogen that induces osteoclast activation independent of its proteolytic activity. We now identify programmed death-1 homolo...
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
Nature Portfolio
2023-07-01
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| Σειρά: | Nature Communications |
| Διαθέσιμο Online: | https://doi.org/10.1038/s41467-023-39769-8 |