Choroidal neovascularization complicating sclerochoroidal calcifications
Purpose: Sclerochoroidal calcifications (SCC) are rare conditions characterized by unifocal or multifocal well-defined scleral deposits of calcium. The present study describes two cases of SCC complicated by the onset of choroidal neovascularization (CNV). Method: Five patients affected by SCC were...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993621002449 |
| _version_ | 1818834963830669312 |
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| author | Maurizio Battaglia Parodi Alessandro Arrigo Adelaide Pina Francesca Calcagno Alessio Antropoli Rashid Hassan Farah Francesco Bandello Ahmad M. Mansour |
| author_facet | Maurizio Battaglia Parodi Alessandro Arrigo Adelaide Pina Francesca Calcagno Alessio Antropoli Rashid Hassan Farah Francesco Bandello Ahmad M. Mansour |
| author_sort | Maurizio Battaglia Parodi |
| collection | DOAJ |
| description | Purpose: Sclerochoroidal calcifications (SCC) are rare conditions characterized by unifocal or multifocal well-defined scleral deposits of calcium. The present study describes two cases of SCC complicated by the onset of choroidal neovascularization (CNV). Method: Five patients affected by SCC were enrolled in the study and two cases were complicated by CNV. Both patients underwent complete ophthalmic examination with multimodal imaging including optical coherence tomography angiography (OCTA). Results: In the two patients with CNV (1 male), BCVA was 20/40 and 20/50 in the affected eyes. Fundus examination revealed an irregular yellow-white lesion close to the superotemporal arcade in both patients, with exudation. The diagnosis of CNV was performed by means of fluorescein angiography in one patient and OCTA in the other patient. The patients received a total of 3 and 9 ranibizumab injections respectively over a six-year follow-up, reaching a final BCVA of 20/25 in both patients with stabilization of the CNV. Conclusions: SCC may be complicated by CNV, with good management obtained by intravitreal anti-VEGF injections. |
| first_indexed | 2024-12-19T02:43:10Z |
| format | Article |
| id | doaj.art-598fcb8d94ad4da1870763aa4fc7c47d |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-19T02:43:10Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-598fcb8d94ad4da1870763aa4fc7c47d2022-12-21T20:39:03ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362021-12-0124101235Choroidal neovascularization complicating sclerochoroidal calcificationsMaurizio Battaglia Parodi0Alessandro Arrigo1Adelaide Pina2Francesca Calcagno3Alessio Antropoli4Rashid Hassan Farah5Francesco Bandello6Ahmad M. Mansour7Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, ItalyDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy; Corresponding author.Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, ItalyDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, ItalyDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, ItalyDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, ItalyDepartment of Ophthalmology, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, ItalyDepartment of Ophthalmology, American University of Beirut, Rafic Hariri University Hospital, P.O. Box 113-6044, Beirut, LebanonPurpose: Sclerochoroidal calcifications (SCC) are rare conditions characterized by unifocal or multifocal well-defined scleral deposits of calcium. The present study describes two cases of SCC complicated by the onset of choroidal neovascularization (CNV). Method: Five patients affected by SCC were enrolled in the study and two cases were complicated by CNV. Both patients underwent complete ophthalmic examination with multimodal imaging including optical coherence tomography angiography (OCTA). Results: In the two patients with CNV (1 male), BCVA was 20/40 and 20/50 in the affected eyes. Fundus examination revealed an irregular yellow-white lesion close to the superotemporal arcade in both patients, with exudation. The diagnosis of CNV was performed by means of fluorescein angiography in one patient and OCTA in the other patient. The patients received a total of 3 and 9 ranibizumab injections respectively over a six-year follow-up, reaching a final BCVA of 20/25 in both patients with stabilization of the CNV. Conclusions: SCC may be complicated by CNV, with good management obtained by intravitreal anti-VEGF injections.http://www.sciencedirect.com/science/article/pii/S2451993621002449Sclerochoroidal calcificationChoroidal neovascularizationOCTOCTAFAFMultimodal imaging |
| spellingShingle | Maurizio Battaglia Parodi Alessandro Arrigo Adelaide Pina Francesca Calcagno Alessio Antropoli Rashid Hassan Farah Francesco Bandello Ahmad M. Mansour Choroidal neovascularization complicating sclerochoroidal calcifications American Journal of Ophthalmology Case Reports Sclerochoroidal calcification Choroidal neovascularization OCT OCTA FAF Multimodal imaging |
| title | Choroidal neovascularization complicating sclerochoroidal calcifications |
| title_full | Choroidal neovascularization complicating sclerochoroidal calcifications |
| title_fullStr | Choroidal neovascularization complicating sclerochoroidal calcifications |
| title_full_unstemmed | Choroidal neovascularization complicating sclerochoroidal calcifications |
| title_short | Choroidal neovascularization complicating sclerochoroidal calcifications |
| title_sort | choroidal neovascularization complicating sclerochoroidal calcifications |
| topic | Sclerochoroidal calcification Choroidal neovascularization OCT OCTA FAF Multimodal imaging |
| url | http://www.sciencedirect.com/science/article/pii/S2451993621002449 |
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