Papain-induced occupational rhinoconjunctivitis and asthma – A case report
This report presents a case of occupational asthma, rhinitis and conjunctivitis to papain in a 50-year-old herbs and spices packer, with documented increased eosinophilia in induced sputum and in the nasal lavage fluids after a specific inhalation challenge test (SICT) and specific nasal challenge t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nofer Institute of Occupational Medicine
2016-04-01
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| Series: | Medycyna Pracy |
| Subjects: | |
| Online Access: | http://medpr.imp.lodz.pl/Papain-induced-occupational-rhinoconjunctivitis-and-asthma-A-case-report,61070,0,2.html |
| _version_ | 1818336096102121472 |
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| author | Diana Tymoszuk Marta Wiszniewska Jolanta Walusiak-Skorupa |
| author_facet | Diana Tymoszuk Marta Wiszniewska Jolanta Walusiak-Skorupa |
| author_sort | Diana Tymoszuk |
| collection | DOAJ |
| description | This report presents a case of occupational asthma, rhinitis and conjunctivitis to papain in a 50-year-old herbs and spices packer, with documented increased eosinophilia in induced sputum and in the nasal lavage fluids after a specific inhalation challenge test (SICT) and specific nasal challenge test (SNCT) with this enzyme. Immunoglobulin E-mediated (IgE) sensitization to papain was confirmed by positive results of a skin prick test with specific solution. Specific inhalation and nasal challenge tests demonstrated a direct and significant link between the exposure to this protease and the allergic response from the respiratory system. Additionally, the SNCT induced a severe reaction of the conjunctivae and a significant increase in the count of eosinophils in tears, despite the lack of direct contact of the allergen with the conjunctiva. Med Pr 2016;67(1):109–112 |
| first_indexed | 2024-12-13T14:33:53Z |
| format | Article |
| id | doaj.art-5993e853f5ea4fe9a03efffe62e8ec7d |
| institution | Directory Open Access Journal |
| issn | 0465-5893 2353-1339 |
| language | English |
| last_indexed | 2024-12-13T14:33:53Z |
| publishDate | 2016-04-01 |
| publisher | Nofer Institute of Occupational Medicine |
| record_format | Article |
| series | Medycyna Pracy |
| spelling | doaj.art-5993e853f5ea4fe9a03efffe62e8ec7d2022-12-21T23:41:46ZengNofer Institute of Occupational MedicineMedycyna Pracy0465-58932353-13392016-04-0167110911210.13075/mp.5893.00317Papain-induced occupational rhinoconjunctivitis and asthma – A case reportDiana TymoszukMarta WiszniewskaJolanta Walusiak-SkorupaThis report presents a case of occupational asthma, rhinitis and conjunctivitis to papain in a 50-year-old herbs and spices packer, with documented increased eosinophilia in induced sputum and in the nasal lavage fluids after a specific inhalation challenge test (SICT) and specific nasal challenge test (SNCT) with this enzyme. Immunoglobulin E-mediated (IgE) sensitization to papain was confirmed by positive results of a skin prick test with specific solution. Specific inhalation and nasal challenge tests demonstrated a direct and significant link between the exposure to this protease and the allergic response from the respiratory system. Additionally, the SNCT induced a severe reaction of the conjunctivae and a significant increase in the count of eosinophils in tears, despite the lack of direct contact of the allergen with the conjunctiva. Med Pr 2016;67(1):109–112http://medpr.imp.lodz.pl/Papain-induced-occupational-rhinoconjunctivitis-and-asthma-A-case-report,61070,0,2.htmlasthmaoccupational allergyenzymerhinitispapainconjunctivitis |
| spellingShingle | Diana Tymoszuk Marta Wiszniewska Jolanta Walusiak-Skorupa Papain-induced occupational rhinoconjunctivitis and asthma – A case report Medycyna Pracy asthma occupational allergy enzyme rhinitis papain conjunctivitis |
| title | Papain-induced occupational rhinoconjunctivitis and asthma – A case report |
| title_full | Papain-induced occupational rhinoconjunctivitis and asthma – A case report |
| title_fullStr | Papain-induced occupational rhinoconjunctivitis and asthma – A case report |
| title_full_unstemmed | Papain-induced occupational rhinoconjunctivitis and asthma – A case report |
| title_short | Papain-induced occupational rhinoconjunctivitis and asthma – A case report |
| title_sort | papain induced occupational rhinoconjunctivitis and asthma a case report |
| topic | asthma occupational allergy enzyme rhinitis papain conjunctivitis |
| url | http://medpr.imp.lodz.pl/Papain-induced-occupational-rhinoconjunctivitis-and-asthma-A-case-report,61070,0,2.html |
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