Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study
Objective:To describe the clinical stage in women diagnosed with breast cancer and the association between clinical stage and Health-related quality of life (HRQoL).Materials and Methods:This was a cross-sectional study involving women diagnosed with breast cancer. HRQoL was assessed with European O...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2019-01-01
|
| Series: | European Journal of Breast Health |
| Subjects: | |
| Online Access: |
http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/advanced-clinical-stage-at-diagnosis-of-breast-can/41969
|
| _version_ | 1797916152947539968 |
|---|---|
| author | Julia de Mello Ramirez Medina Ingrid de Araujo Trugilho Giovanna Nunes Belo Mendes Josiel Guedes Silva Maria Alexsandra da Silva Paiva Suzana Sales de Aguiar Luiz Claudio Santos Thuler Anke Bergmann |
| author_facet | Julia de Mello Ramirez Medina Ingrid de Araujo Trugilho Giovanna Nunes Belo Mendes Josiel Guedes Silva Maria Alexsandra da Silva Paiva Suzana Sales de Aguiar Luiz Claudio Santos Thuler Anke Bergmann |
| author_sort | Julia de Mello Ramirez Medina |
| collection | DOAJ |
| description | Objective:To describe the clinical stage in women diagnosed with breast cancer and the association between clinical stage and Health-related quality of life (HRQoL).Materials and Methods:This was a cross-sectional study involving women diagnosed with breast cancer. HRQoL was assessed with European Organization for Research and Treatment of Cancer 30-Item Quality of Life Questionnaire and the Quality of Life Questionnaire Breast Cancer 23. The principal exposure was clinical stage (<IIB versus ≥IIB). Simple linear regression was performed and variables with p<0.20 were selected for the multiple linear regression. The final model was composed of statistically significant variables (p<0.05).Results:In total, 302 women were included. The majority (58.9%) had been diagnosed with advanced stage cancer (≥IIB). Those at an advanced clinical stage had poorer role functioning (p=0.029), pain (p<0.001), and symptoms in the breast (p<0.001).Conclusion:Advanced clinical stage at diagnosis was found to be associated with worse health-related quality of life in breast cancer patients. |
| first_indexed | 2024-04-10T12:52:41Z |
| format | Article |
| id | doaj.art-59988aab10554bfb99e3b2af9309ef78 |
| institution | Directory Open Access Journal |
| issn | 2587-0831 |
| language | English |
| last_indexed | 2024-04-10T12:52:41Z |
| publishDate | 2019-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | European Journal of Breast Health |
| spelling | doaj.art-59988aab10554bfb99e3b2af9309ef782023-02-15T16:13:39ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312019-01-01151263110.5152/ejbh.2018.429713049054Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional StudyJulia de Mello Ramirez Medina0Ingrid de Araujo Trugilho1Giovanna Nunes Belo Mendes2Josiel Guedes Silva3Maria Alexsandra da Silva Paiva4Suzana Sales de Aguiar5Luiz Claudio Santos Thuler6Anke Bergmann7 Department of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil Department of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil CEUMA University, Maranhão, Brazil Federal University of Maranhão, Maranhão, Brazil Estácio College of Amazonas, Manaus, Brazil Department of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil Department of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil Department of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil Objective:To describe the clinical stage in women diagnosed with breast cancer and the association between clinical stage and Health-related quality of life (HRQoL).Materials and Methods:This was a cross-sectional study involving women diagnosed with breast cancer. HRQoL was assessed with European Organization for Research and Treatment of Cancer 30-Item Quality of Life Questionnaire and the Quality of Life Questionnaire Breast Cancer 23. The principal exposure was clinical stage (<IIB versus ≥IIB). Simple linear regression was performed and variables with p<0.20 were selected for the multiple linear regression. The final model was composed of statistically significant variables (p<0.05).Results:In total, 302 women were included. The majority (58.9%) had been diagnosed with advanced stage cancer (≥IIB). Those at an advanced clinical stage had poorer role functioning (p=0.029), pain (p<0.001), and symptoms in the breast (p<0.001).Conclusion:Advanced clinical stage at diagnosis was found to be associated with worse health-related quality of life in breast cancer patients. http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/advanced-clinical-stage-at-diagnosis-of-breast-can/41969 breast neoplasmquality of lifeneoplasm staging |
| spellingShingle | Julia de Mello Ramirez Medina Ingrid de Araujo Trugilho Giovanna Nunes Belo Mendes Josiel Guedes Silva Maria Alexsandra da Silva Paiva Suzana Sales de Aguiar Luiz Claudio Santos Thuler Anke Bergmann Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study European Journal of Breast Health breast neoplasm quality of life neoplasm staging |
| title | Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study |
| title_full | Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study |
| title_fullStr | Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study |
| title_full_unstemmed | Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study |
| title_short | Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study |
| title_sort | advanced clinical stage at diagnosis of breast cancer is associated with poorer health related quality of life a cross sectional study |
| topic | breast neoplasm quality of life neoplasm staging |
| url |
http://www.eurjbreasthealth.com/archives/archive-detail/article-preview/advanced-clinical-stage-at-diagnosis-of-breast-can/41969
|
| work_keys_str_mv | AT juliademelloramirezmedina advancedclinicalstageatdiagnosisofbreastcancerisassociatedwithpoorerhealthrelatedqualityoflifeacrosssectionalstudy AT ingriddearaujotrugilho advancedclinicalstageatdiagnosisofbreastcancerisassociatedwithpoorerhealthrelatedqualityoflifeacrosssectionalstudy AT giovannanunesbelomendes advancedclinicalstageatdiagnosisofbreastcancerisassociatedwithpoorerhealthrelatedqualityoflifeacrosssectionalstudy AT josielguedessilva advancedclinicalstageatdiagnosisofbreastcancerisassociatedwithpoorerhealthrelatedqualityoflifeacrosssectionalstudy AT mariaalexsandradasilvapaiva advancedclinicalstageatdiagnosisofbreastcancerisassociatedwithpoorerhealthrelatedqualityoflifeacrosssectionalstudy AT suzanasalesdeaguiar advancedclinicalstageatdiagnosisofbreastcancerisassociatedwithpoorerhealthrelatedqualityoflifeacrosssectionalstudy AT luizclaudiosantosthuler advancedclinicalstageatdiagnosisofbreastcancerisassociatedwithpoorerhealthrelatedqualityoflifeacrosssectionalstudy AT ankebergmann advancedclinicalstageatdiagnosisofbreastcancerisassociatedwithpoorerhealthrelatedqualityoflifeacrosssectionalstudy |