Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review
The coronavirus disease 2019 (COVID-19) pandemic has had profound and lasting consequences since 2019. Although vaccines against COVID-19 have been developed and approved under emergency use authorization, various adverse events have also been reported after COVID-19 vaccination. This review was und...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
|
| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/9/12/1404 |
| _version_ | 1797500037044895744 |
|---|---|
| author | Yu-Kuei Lee Yi-Hsun Huang |
| author_facet | Yu-Kuei Lee Yi-Hsun Huang |
| author_sort | Yu-Kuei Lee |
| collection | DOAJ |
| description | The coronavirus disease 2019 (COVID-19) pandemic has had profound and lasting consequences since 2019. Although vaccines against COVID-19 have been developed and approved under emergency use authorization, various adverse events have also been reported after COVID-19 vaccination. This review was undertaken to help clinicians recognize the possible manifestations and systemic pathogenesis, especially those related to the eye, after receiving COVID-19 vaccination. A systemic search was performed on 22 August 2021 through Embase, Medline, and Cochrane Library for publications on ocular manifestations after COVID-19 vaccination. Two case-control studies/retrospective cohort studies, one cross-sectional study, three case series, sixteen case reports, two images, and seven letters were included. Ocular manifestations after receiving COVID-19 vaccines may appear on the eyelid, cornea and ocular surface, retina, uvea, nerve, and vessel. The ocular manifestations occurred up to forty-two days after vaccination, and vaccine-induced immunologic responses may be responsible. Although the incidence rate of ocular symptoms is considerably lower in the vaccinated subjects than in COVID-19 patients, physicians should be aware of the possible associations between COVID-19 vaccines and ocular symptoms for the early diagnosis and treatment of vision problems or life-threatening complications. |
| first_indexed | 2024-03-10T03:56:03Z |
| format | Article |
| id | doaj.art-599a83d4e91c42b0954f71d4dfa26f92 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T03:56:03Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-599a83d4e91c42b0954f71d4dfa26f922023-11-23T10:53:53ZengMDPI AGVaccines2076-393X2021-11-01912140410.3390/vaccines9121404Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic ReviewYu-Kuei Lee0Yi-Hsun Huang1Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, TaiwanDepartment of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, TaiwanThe coronavirus disease 2019 (COVID-19) pandemic has had profound and lasting consequences since 2019. Although vaccines against COVID-19 have been developed and approved under emergency use authorization, various adverse events have also been reported after COVID-19 vaccination. This review was undertaken to help clinicians recognize the possible manifestations and systemic pathogenesis, especially those related to the eye, after receiving COVID-19 vaccination. A systemic search was performed on 22 August 2021 through Embase, Medline, and Cochrane Library for publications on ocular manifestations after COVID-19 vaccination. Two case-control studies/retrospective cohort studies, one cross-sectional study, three case series, sixteen case reports, two images, and seven letters were included. Ocular manifestations after receiving COVID-19 vaccines may appear on the eyelid, cornea and ocular surface, retina, uvea, nerve, and vessel. The ocular manifestations occurred up to forty-two days after vaccination, and vaccine-induced immunologic responses may be responsible. Although the incidence rate of ocular symptoms is considerably lower in the vaccinated subjects than in COVID-19 patients, physicians should be aware of the possible associations between COVID-19 vaccines and ocular symptoms for the early diagnosis and treatment of vision problems or life-threatening complications.https://www.mdpi.com/2076-393X/9/12/1404adverse eventscoronavirus disease 2019 (COVID-19)ophthalmologyvaccines |
| spellingShingle | Yu-Kuei Lee Yi-Hsun Huang Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review Vaccines adverse events coronavirus disease 2019 (COVID-19) ophthalmology vaccines |
| title | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
| title_full | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
| title_fullStr | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
| title_full_unstemmed | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
| title_short | Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review |
| title_sort | ocular manifestations after receiving covid 19 vaccine a systematic review |
| topic | adverse events coronavirus disease 2019 (COVID-19) ophthalmology vaccines |
| url | https://www.mdpi.com/2076-393X/9/12/1404 |
| work_keys_str_mv | AT yukueilee ocularmanifestationsafterreceivingcovid19vaccineasystematicreview AT yihsunhuang ocularmanifestationsafterreceivingcovid19vaccineasystematicreview |