A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates

A powerful tool for the analysis of nonrandomized observational studies has been the potential outcomes model. Utilization of this framework allows analysts to estimate average treatment effects. This article considers the situation in which high-dimensional covariates are present and revisits the s...

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Main Authors: Ghosh Debashis, Cruz Cortés Efrén
Format: Article
Language:English
Published: De Gruyter 2019-09-01
Series:Journal of Causal Inference
Subjects:
Online Access:https://doi.org/10.1515/jci-2018-0024
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author Ghosh Debashis
Cruz Cortés Efrén
author_facet Ghosh Debashis
Cruz Cortés Efrén
author_sort Ghosh Debashis
collection DOAJ
description A powerful tool for the analysis of nonrandomized observational studies has been the potential outcomes model. Utilization of this framework allows analysts to estimate average treatment effects. This article considers the situation in which high-dimensional covariates are present and revisits the standard assumptions made in causal inference. We show that by employing a flexible Gaussian process framework, the assumption of strict overlap leads to very restrictive assumptions about the distribution of covariates, results for which can be characterized using classical results from Gaussian random measures as well as reproducing kernel Hilbert space theory. In addition, we propose a strategy for data-adaptive causal effect estimation that does not rely on the strict overlap assumption. These findings reveal under a focused framework the stringency that accompanies the use of the treatment positivity assumption in high-dimensional settings.
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spelling doaj.art-599ba7e0f70b442885c02274404666922022-12-21T22:07:55ZengDe GruyterJournal of Causal Inference2193-36772193-36852019-09-017273536010.1515/jci-2018-0024A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional CovariatesGhosh Debashis0Cruz Cortés Efrén1Department of Biostatistics and Informatics, 144805Colorado School of Public Health, 80045Aurora, CO, United StatesDepartment of Biostatistics and Informatics, 144805Colorado School of Public Health, 80045Aurora, CO, United StatesA powerful tool for the analysis of nonrandomized observational studies has been the potential outcomes model. Utilization of this framework allows analysts to estimate average treatment effects. This article considers the situation in which high-dimensional covariates are present and revisits the standard assumptions made in causal inference. We show that by employing a flexible Gaussian process framework, the assumption of strict overlap leads to very restrictive assumptions about the distribution of covariates, results for which can be characterized using classical results from Gaussian random measures as well as reproducing kernel Hilbert space theory. In addition, we propose a strategy for data-adaptive causal effect estimation that does not rely on the strict overlap assumption. These findings reveal under a focused framework the stringency that accompanies the use of the treatment positivity assumption in high-dimensional settings.https://doi.org/10.1515/jci-2018-0024average causal effectcovariate balancefunctional datamachine learningpositivity
spellingShingle Ghosh Debashis
Cruz Cortés Efrén
A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates
Journal of Causal Inference
average causal effect
covariate balance
functional data
machine learning
positivity
title A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates
title_full A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates
title_fullStr A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates
title_full_unstemmed A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates
title_short A Gaussian Process Framework for Overlap and Causal Effect Estimation with High-Dimensional Covariates
title_sort gaussian process framework for overlap and causal effect estimation with high dimensional covariates
topic average causal effect
covariate balance
functional data
machine learning
positivity
url https://doi.org/10.1515/jci-2018-0024
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