Mapping the Glymphatic Pathway Using Imaging Advances
The glymphatic system is a newly discovered waste-clearing system that is analogous to the lymphatic system in our central nervous system. Furthermore, disruption in the glymphatic system has also been associated with many neurodegenerative disorders (e.g., Alzheimer’s disease), traumatic brain inju...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-08-01
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| Series: | J |
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| Online Access: | https://www.mdpi.com/2571-8800/6/3/31 |
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| author | Rajvi N. Thakkar Ivelina P. Kioutchoukova Ian Griffin Devon T. Foster Pratiksha Sharma Eduardo Molina Valero Brandon Lucke-Wold |
| author_facet | Rajvi N. Thakkar Ivelina P. Kioutchoukova Ian Griffin Devon T. Foster Pratiksha Sharma Eduardo Molina Valero Brandon Lucke-Wold |
| author_sort | Rajvi N. Thakkar |
| collection | DOAJ |
| description | The glymphatic system is a newly discovered waste-clearing system that is analogous to the lymphatic system in our central nervous system. Furthermore, disruption in the glymphatic system has also been associated with many neurodegenerative disorders (e.g., Alzheimer’s disease), traumatic brain injury, and subarachnoid hemorrhage. Thus, understanding the function and structure of this system can play a key role in researching the progression and prognoses of these diseases. In this review article, we discuss the current ways to map the glymphatic system and address the advances being made in preclinical mapping. As mentioned, the concept of the glymphatic system is relatively new, and thus, more research needs to be conducted in order to therapeutically intervene via this system. |
| first_indexed | 2024-03-10T22:38:08Z |
| format | Article |
| id | doaj.art-59a3094179824e04a5b2d54bf243653e |
| institution | Directory Open Access Journal |
| issn | 2571-8800 |
| language | English |
| last_indexed | 2024-03-10T22:38:08Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | J |
| spelling | doaj.art-59a3094179824e04a5b2d54bf243653e2023-11-19T11:16:10ZengMDPI AGJ2571-88002023-08-016347749110.3390/j6030031Mapping the Glymphatic Pathway Using Imaging AdvancesRajvi N. Thakkar0Ivelina P. Kioutchoukova1Ian Griffin2Devon T. Foster3Pratiksha Sharma4Eduardo Molina Valero5Brandon Lucke-Wold6College of Medicine, University of Florida, Gainesville, FL 32610, USACollege of Medicine, University of Florida, Gainesville, FL 32610, USACollege of Medicine, University of Florida, Gainesville, FL 32610, USACollege of Medicine, Florida International University, Miami, FL 33199, USAThermo Fisher Scientific Inc., Boston, MA 02210, USACollege of Medicine, University of Florida, Gainesville, FL 32610, USADepartment of Neurosurgery, University of Florida, 1600 SW Archer Rd., Gainesville, FL 32610, USAThe glymphatic system is a newly discovered waste-clearing system that is analogous to the lymphatic system in our central nervous system. Furthermore, disruption in the glymphatic system has also been associated with many neurodegenerative disorders (e.g., Alzheimer’s disease), traumatic brain injury, and subarachnoid hemorrhage. Thus, understanding the function and structure of this system can play a key role in researching the progression and prognoses of these diseases. In this review article, we discuss the current ways to map the glymphatic system and address the advances being made in preclinical mapping. As mentioned, the concept of the glymphatic system is relatively new, and thus, more research needs to be conducted in order to therapeutically intervene via this system.https://www.mdpi.com/2571-8800/6/3/31glymphatic systemmagnetic resonance imaging (MRI) sequencingimaging techniquesneurological diseases |
| spellingShingle | Rajvi N. Thakkar Ivelina P. Kioutchoukova Ian Griffin Devon T. Foster Pratiksha Sharma Eduardo Molina Valero Brandon Lucke-Wold Mapping the Glymphatic Pathway Using Imaging Advances J glymphatic system magnetic resonance imaging (MRI) sequencing imaging techniques neurological diseases |
| title | Mapping the Glymphatic Pathway Using Imaging Advances |
| title_full | Mapping the Glymphatic Pathway Using Imaging Advances |
| title_fullStr | Mapping the Glymphatic Pathway Using Imaging Advances |
| title_full_unstemmed | Mapping the Glymphatic Pathway Using Imaging Advances |
| title_short | Mapping the Glymphatic Pathway Using Imaging Advances |
| title_sort | mapping the glymphatic pathway using imaging advances |
| topic | glymphatic system magnetic resonance imaging (MRI) sequencing imaging techniques neurological diseases |
| url | https://www.mdpi.com/2571-8800/6/3/31 |
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