Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritis
PurposeTo evaluate the diagnostic value of the Vesikari Scoring System (VSS) as an early predictor of pathogens in children with acute gastroenteritis (AG).MethodsIn this retrospective study, the VSS score, absolute neutrophil count (ANC), and C-reactive protein (CRP) levels were analyzed in 107 hos...
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| Format: | Article |
| Language: | English |
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Korean Pediatric Society
2016-03-01
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| Series: | Korean Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://kjp.or.kr/upload/pdf/kjped-59-126.pdf |
| _version_ | 1818192534889824256 |
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| author | Dong Ho Shim Dong Yeon Kim Ky Young Cho |
| author_facet | Dong Ho Shim Dong Yeon Kim Ky Young Cho |
| author_sort | Dong Ho Shim |
| collection | DOAJ |
| description | PurposeTo evaluate the diagnostic value of the Vesikari Scoring System (VSS) as an early predictor of pathogens in children with acute gastroenteritis (AG).MethodsIn this retrospective study, the VSS score, absolute neutrophil count (ANC), and C-reactive protein (CRP) levels were analyzed in 107 hospitalized children with AG, aged 6 months to 17 years. Patients were divided into nonspecific, viral, and bacterial groups according to the pathogens detected using a multiplex polymerase chain reaction (PCR) test.ResultsPatients in the bacterial group had significantly higher CRP values and VSS scores compared to those in the viral group and significantly higher VSS scores compared to those in the nonspecific group (P<0.05). Patients in the viral group had significantly higher VSS scores than those in the nonspecific group (P<0.05). Logistic regression analysis revealed that VSS was the most effective diagnostic tool for predicting the type of pathogen (P<0.05). The area under the receiver operating characteristics curve of VSS was significantly greater than that for ANC and CRP (P<0.05). At a cutoff point of 10 in the VSS, an acceptable diagnostic accuracy could be achieved for distinguishing between bacterial and viral pathogens in AG.ConclusionVSS can be considered a useful and reliable infectious marker for pediatric gastroenteritis. VSS may be a good early predictor of the type of pathogen, enabling development of a treatment plan before results from a stool culture or PCR test are available. |
| first_indexed | 2024-12-12T00:32:02Z |
| format | Article |
| id | doaj.art-59a880a0fdef45f9b95748751b8edc18 |
| institution | Directory Open Access Journal |
| issn | 1738-1061 2092-7258 |
| language | English |
| last_indexed | 2024-12-12T00:32:02Z |
| publishDate | 2016-03-01 |
| publisher | Korean Pediatric Society |
| record_format | Article |
| series | Korean Journal of Pediatrics |
| spelling | doaj.art-59a880a0fdef45f9b95748751b8edc182022-12-22T00:44:27ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582016-03-0159312613110.3345/kjp.2016.59.3.12620125550524Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritisDong Ho Shim0Dong Yeon Kim1Ky Young Cho2Department of Pediatrics, KEPCO Medical Center, Seoul, Korea.Department of Pediatrics, KEPCO Medical Center, Seoul, Korea.Department of Pediatrics, KEPCO Medical Center, Seoul, Korea.PurposeTo evaluate the diagnostic value of the Vesikari Scoring System (VSS) as an early predictor of pathogens in children with acute gastroenteritis (AG).MethodsIn this retrospective study, the VSS score, absolute neutrophil count (ANC), and C-reactive protein (CRP) levels were analyzed in 107 hospitalized children with AG, aged 6 months to 17 years. Patients were divided into nonspecific, viral, and bacterial groups according to the pathogens detected using a multiplex polymerase chain reaction (PCR) test.ResultsPatients in the bacterial group had significantly higher CRP values and VSS scores compared to those in the viral group and significantly higher VSS scores compared to those in the nonspecific group (P<0.05). Patients in the viral group had significantly higher VSS scores than those in the nonspecific group (P<0.05). Logistic regression analysis revealed that VSS was the most effective diagnostic tool for predicting the type of pathogen (P<0.05). The area under the receiver operating characteristics curve of VSS was significantly greater than that for ANC and CRP (P<0.05). At a cutoff point of 10 in the VSS, an acceptable diagnostic accuracy could be achieved for distinguishing between bacterial and viral pathogens in AG.ConclusionVSS can be considered a useful and reliable infectious marker for pediatric gastroenteritis. VSS may be a good early predictor of the type of pathogen, enabling development of a treatment plan before results from a stool culture or PCR test are available.http://kjp.or.kr/upload/pdf/kjped-59-126.pdfChildGastroenteritisRelative value scalesNeutrophilsC-reactive protein |
| spellingShingle | Dong Ho Shim Dong Yeon Kim Ky Young Cho Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritis Korean Journal of Pediatrics Child Gastroenteritis Relative value scales Neutrophils C-reactive protein |
| title | Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritis |
| title_full | Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritis |
| title_fullStr | Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritis |
| title_full_unstemmed | Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritis |
| title_short | Diagnostic value of the Vesikari Scoring System for predicting the viral or bacterial pathogens in pediatric gastroenteritis |
| title_sort | diagnostic value of the vesikari scoring system for predicting the viral or bacterial pathogens in pediatric gastroenteritis |
| topic | Child Gastroenteritis Relative value scales Neutrophils C-reactive protein |
| url | http://kjp.or.kr/upload/pdf/kjped-59-126.pdf |
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