Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers’ Cohort Study
The aim of the present study was to derive dietary patterns to explain variation in a set of nutrient intakes or in the measurements of waist circumference (WC) and fasting blood glucose (FBG) using reduced rank regression (RRR) and to prospectively investigate these patterns in relation to the risk...
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MDPI AG
2022-07-01
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| Online Access: | https://www.mdpi.com/2072-6643/14/15/3019 |
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| author | Yuanying Li Hiroshi Yatsuya Chaochen Wang Mayu Uemura Masaaki Matsunaga Yupeng He Maythet Khine Atsuhiko Ota |
| author_facet | Yuanying Li Hiroshi Yatsuya Chaochen Wang Mayu Uemura Masaaki Matsunaga Yupeng He Maythet Khine Atsuhiko Ota |
| author_sort | Yuanying Li |
| collection | DOAJ |
| description | The aim of the present study was to derive dietary patterns to explain variation in a set of nutrient intakes or in the measurements of waist circumference (WC) and fasting blood glucose (FBG) using reduced rank regression (RRR) and to prospectively investigate these patterns in relation to the risk of developing metabolic syndrome (MetS) and its components during the follow-up. The study participants were comprised of 2944 government employees aged 30–59 years without MetS. RRR was applied with 38 food groups as predictors and with two sets of response variables. The first set included intake of putatively beneficial nutrients, and the first factor retained was named the Healthy Dietary Pattern (HDP). The second one included baseline WC and FBG, and the first factor was named the Unhealthy Dietary Pattern (UHDP). Multivariable Cox proportional hazard model was used to estimate hazard ratio and 95% confidence intervals with adjustments for age, sex, total energy consumption and other potential confounders. During the 5-year median follow-up, we ascertained 374 cases of MetS. The HDP score was inversely associated with the incidence of MetS (<i>p</i>-trend = 0.009) and hypertension (<i>p</i>-trend = 0.002) and marginally significantly associated with elevated triglyceride and decreased high-density lipoprotein cholesterol (<i>p</i>-trend = 0.08). The UHDP score was linearly positively associated with the incidence of MetS and all its components (all <i>p</i>-trend < 0.05). Both the HDP and UHDP predicted the development of MetS and its components. |
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| last_indexed | 2024-03-09T12:18:48Z |
| publishDate | 2022-07-01 |
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| series | Nutrients |
| spelling | doaj.art-59aac0a1a3e34814a3f3e8ebd254c9c12023-11-30T22:43:30ZengMDPI AGNutrients2072-66432022-07-011415301910.3390/nu14153019Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers’ Cohort StudyYuanying Li0Hiroshi Yatsuya1Chaochen Wang2Mayu Uemura3Masaaki Matsunaga4Yupeng He5Maythet Khine6Atsuhiko Ota7Department of Public Health, Fujita Health University School of Medicine, Toyoake 470-1192, JapanDepartment of Public Health and Health Systems, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanJapan Value, Evidence and Outcomes, Japan Drug Development and Medical Affairs, Eli Lilly Japan K.K., Kobe 651-0086, JapanDepartment of Public Health and Health Systems, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Public Health, Fujita Health University School of Medicine, Toyoake 470-1192, JapanDepartment of Public Health, Fujita Health University School of Medicine, Toyoake 470-1192, JapanDepartment of Public Health, Fujita Health University School of Medicine, Toyoake 470-1192, JapanDepartment of Public Health, Fujita Health University School of Medicine, Toyoake 470-1192, JapanThe aim of the present study was to derive dietary patterns to explain variation in a set of nutrient intakes or in the measurements of waist circumference (WC) and fasting blood glucose (FBG) using reduced rank regression (RRR) and to prospectively investigate these patterns in relation to the risk of developing metabolic syndrome (MetS) and its components during the follow-up. The study participants were comprised of 2944 government employees aged 30–59 years without MetS. RRR was applied with 38 food groups as predictors and with two sets of response variables. The first set included intake of putatively beneficial nutrients, and the first factor retained was named the Healthy Dietary Pattern (HDP). The second one included baseline WC and FBG, and the first factor was named the Unhealthy Dietary Pattern (UHDP). Multivariable Cox proportional hazard model was used to estimate hazard ratio and 95% confidence intervals with adjustments for age, sex, total energy consumption and other potential confounders. During the 5-year median follow-up, we ascertained 374 cases of MetS. The HDP score was inversely associated with the incidence of MetS (<i>p</i>-trend = 0.009) and hypertension (<i>p</i>-trend = 0.002) and marginally significantly associated with elevated triglyceride and decreased high-density lipoprotein cholesterol (<i>p</i>-trend = 0.08). The UHDP score was linearly positively associated with the incidence of MetS and all its components (all <i>p</i>-trend < 0.05). Both the HDP and UHDP predicted the development of MetS and its components.https://www.mdpi.com/2072-6643/14/15/3019dietary patternnutrientsmetabolic syndromeprospectiveworkerreduced rank regression |
| spellingShingle | Yuanying Li Hiroshi Yatsuya Chaochen Wang Mayu Uemura Masaaki Matsunaga Yupeng He Maythet Khine Atsuhiko Ota Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers’ Cohort Study Nutrients dietary pattern nutrients metabolic syndrome prospective worker reduced rank regression |
| title | Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers’ Cohort Study |
| title_full | Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers’ Cohort Study |
| title_fullStr | Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers’ Cohort Study |
| title_full_unstemmed | Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers’ Cohort Study |
| title_short | Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers’ Cohort Study |
| title_sort | dietary patterns derived from reduced rank regression are associated with the 5 year occurrence of metabolic syndrome aichi workers cohort study |
| topic | dietary pattern nutrients metabolic syndrome prospective worker reduced rank regression |
| url | https://www.mdpi.com/2072-6643/14/15/3019 |
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