Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report
Parry-Romberg Syndrome (PRS) is a rare neurocutaneous disorder characterized by gradual facial hemiatrophy. We present a case study of a 64-year-old woman with late-onset PRS and linear scleroderma. The patient exhibited atypical PRS symptoms including leg numbness, hyper-reflexia, trigeminal neural...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043323007756 |
| _version_ | 1827636279906402304 |
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| author | Sema Akkus, MD Suban Amatya, MD Kriti Shrestha, MD Shitiz Sriwastava, MD Demetrios A. Karides, MD |
| author_facet | Sema Akkus, MD Suban Amatya, MD Kriti Shrestha, MD Shitiz Sriwastava, MD Demetrios A. Karides, MD |
| author_sort | Sema Akkus, MD |
| collection | DOAJ |
| description | Parry-Romberg Syndrome (PRS) is a rare neurocutaneous disorder characterized by gradual facial hemiatrophy. We present a case study of a 64-year-old woman with late-onset PRS and linear scleroderma. The patient exhibited atypical PRS symptoms including leg numbness, hyper-reflexia, trigeminal neuralgia, and severe headaches. Diagnostic evaluations revealed chronic left-sided cerebral infarction, microhemorrhages, and nerve involvement. Treatment options for PRS are limited and aim to manage symptoms. This case highlights the diagnostic challenges of late-onset PRS, emphasizing interdisciplinary approach. Further research and improved therapies are essential for better patient outcomes. |
| first_indexed | 2024-03-09T15:40:47Z |
| format | Article |
| id | doaj.art-59ae3ddd05c3441894363919fcc2975a |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-03-09T15:40:47Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-59ae3ddd05c3441894363919fcc2975a2023-11-25T04:47:33ZengElsevierRadiology Case Reports1930-04332024-01-01191459463Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case reportSema Akkus, MD0Suban Amatya, MD1Kriti Shrestha, MD2Shitiz Sriwastava, MD3Demetrios A. Karides, MD4Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USADepartment of Medicine, Patan Academy of Health Sciences, Lalitpur, Nepal; Corresponding author.Department of Medicine, Patan Academy of Health Sciences, Lalitpur, NepalDivision of Multiple Sclerosis and Neuroimmunology, Department of Neurology, McGovern Medical School (UT Health), University of Texas Health Science Center at Houston, Houston, TX, USADepartment of Neurology, Mount Sinai Health System, New York, NY, USAParry-Romberg Syndrome (PRS) is a rare neurocutaneous disorder characterized by gradual facial hemiatrophy. We present a case study of a 64-year-old woman with late-onset PRS and linear scleroderma. The patient exhibited atypical PRS symptoms including leg numbness, hyper-reflexia, trigeminal neuralgia, and severe headaches. Diagnostic evaluations revealed chronic left-sided cerebral infarction, microhemorrhages, and nerve involvement. Treatment options for PRS are limited and aim to manage symptoms. This case highlights the diagnostic challenges of late-onset PRS, emphasizing interdisciplinary approach. Further research and improved therapies are essential for better patient outcomes.http://www.sciencedirect.com/science/article/pii/S1930043323007756Parry-Romberg syndromeProgressive facial hemiatrophyNeuroimagingBrain MRILate-onsetAtypical manifestations |
| spellingShingle | Sema Akkus, MD Suban Amatya, MD Kriti Shrestha, MD Shitiz Sriwastava, MD Demetrios A. Karides, MD Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report Radiology Case Reports Parry-Romberg syndrome Progressive facial hemiatrophy Neuroimaging Brain MRI Late-onset Atypical manifestations |
| title | Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report |
| title_full | Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report |
| title_fullStr | Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report |
| title_full_unstemmed | Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report |
| title_short | Late-onset Parry-Romberg Syndrome with atypical neurological manifestations: A case report |
| title_sort | late onset parry romberg syndrome with atypical neurological manifestations a case report |
| topic | Parry-Romberg syndrome Progressive facial hemiatrophy Neuroimaging Brain MRI Late-onset Atypical manifestations |
| url | http://www.sciencedirect.com/science/article/pii/S1930043323007756 |
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