Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up
Abstract Purpose To evaluate the efficacy and safety of radiofrequency ablation (RFA) for treating calcified benign thyroid nodules (CBTNs). Methods Fifty-two patients with 52 CBTNs who underwent RFA in our hospital were included in this retrospective study. According to the size of calcifications,...
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| Language: | English |
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BMC
2022-04-01
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| Series: | BMC Medical Imaging |
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| Online Access: | https://doi.org/10.1186/s12880-022-00795-5 |
| _version_ | 1818523837589880832 |
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| author | Yi Li Hongying He Wen Li Jiahang Zhao Naiqiao Ge Yan Zhang Yukun Luo |
| author_facet | Yi Li Hongying He Wen Li Jiahang Zhao Naiqiao Ge Yan Zhang Yukun Luo |
| author_sort | Yi Li |
| collection | DOAJ |
| description | Abstract Purpose To evaluate the efficacy and safety of radiofrequency ablation (RFA) for treating calcified benign thyroid nodules (CBTNs). Methods Fifty-two patients with 52 CBTNs who underwent RFA in our hospital were included in this retrospective study. According to the size of calcifications, CBTNs were divided into two groups: the punctate echogenic foci (PEF) group and macrocalcification group. Moreover, the macrocalcification group was further subdivided into two groups, the strong group and the weak group, based on their morphologic characteristics. After the RFA procedure, routine ultrasound (US) and clinical evaluation were performed at 1, 3, 6 and 12 months postoperatively and every 12 months thereafter. Results The mean follow-up time was 68.98 ± 7.68 months (60–87 months), and the 5-year mean volume reduction rate (VRR) after RFA was 92.95%, with a complication rate of 0.6% (3/52). The mean initial volume of the macrocalcification group was significantly larger than that of the PEF group (9.94 ± 24.60 ml vs. 0.23 ± 0.22 ml, respectively; P = 0.011). Thus, their VRRs were not comparable between the two groups. However, baseline characteristics did not show statistically significant differences between the strong and weak macrocalcification subgroups. The VRRs of the strong subgroup were significantly lower than those of the weak subgroup at the 3-year, 4-year, and 5-year follow-ups. Conclusion RFA was effective and safe for treating CBTNs. Strong macrocalcification was related to the VRR of CBTNs after the RFA procedure. |
| first_indexed | 2024-12-11T05:49:39Z |
| format | Article |
| id | doaj.art-59af89641b1d42ca9c3464aee01d8775 |
| institution | Directory Open Access Journal |
| issn | 1471-2342 |
| language | English |
| last_indexed | 2024-12-11T05:49:39Z |
| publishDate | 2022-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Imaging |
| spelling | doaj.art-59af89641b1d42ca9c3464aee01d87752022-12-22T01:18:51ZengBMCBMC Medical Imaging1471-23422022-04-0122111010.1186/s12880-022-00795-5Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-upYi Li0Hongying He1Wen Li2Jiahang Zhao3Naiqiao Ge4Yan Zhang5Yukun Luo6Department of Ultrasound, Medical School of Chinese PLADepartment of Ultrasound, the First Medical Centre, Chinese PLA General HospitalDepartment of Ultrasound, Medical School of Chinese PLADepartment of Ultrasound, Medical School of Chinese PLADepartment of Ultrasound, Medical School of Chinese PLADepartment of Ultrasound, the First Medical Centre, Chinese PLA General HospitalDepartment of Ultrasound, the First Medical Centre, Chinese PLA General HospitalAbstract Purpose To evaluate the efficacy and safety of radiofrequency ablation (RFA) for treating calcified benign thyroid nodules (CBTNs). Methods Fifty-two patients with 52 CBTNs who underwent RFA in our hospital were included in this retrospective study. According to the size of calcifications, CBTNs were divided into two groups: the punctate echogenic foci (PEF) group and macrocalcification group. Moreover, the macrocalcification group was further subdivided into two groups, the strong group and the weak group, based on their morphologic characteristics. After the RFA procedure, routine ultrasound (US) and clinical evaluation were performed at 1, 3, 6 and 12 months postoperatively and every 12 months thereafter. Results The mean follow-up time was 68.98 ± 7.68 months (60–87 months), and the 5-year mean volume reduction rate (VRR) after RFA was 92.95%, with a complication rate of 0.6% (3/52). The mean initial volume of the macrocalcification group was significantly larger than that of the PEF group (9.94 ± 24.60 ml vs. 0.23 ± 0.22 ml, respectively; P = 0.011). Thus, their VRRs were not comparable between the two groups. However, baseline characteristics did not show statistically significant differences between the strong and weak macrocalcification subgroups. The VRRs of the strong subgroup were significantly lower than those of the weak subgroup at the 3-year, 4-year, and 5-year follow-ups. Conclusion RFA was effective and safe for treating CBTNs. Strong macrocalcification was related to the VRR of CBTNs after the RFA procedure.https://doi.org/10.1186/s12880-022-00795-5Radiofrequency ablationMoving shot techniqueBenign thyroid noduleCalcificationVolume reduction rate |
| spellingShingle | Yi Li Hongying He Wen Li Jiahang Zhao Naiqiao Ge Yan Zhang Yukun Luo Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up BMC Medical Imaging Radiofrequency ablation Moving shot technique Benign thyroid nodule Calcification Volume reduction rate |
| title | Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up |
| title_full | Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up |
| title_fullStr | Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up |
| title_full_unstemmed | Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up |
| title_short | Efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules: results of over 5 years' follow-up |
| title_sort | efficacy and safety of radiofrequency ablation for calcified benign thyroid nodules results of over 5 years follow up |
| topic | Radiofrequency ablation Moving shot technique Benign thyroid nodule Calcification Volume reduction rate |
| url | https://doi.org/10.1186/s12880-022-00795-5 |
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