Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort study
ObjectivesLow cardiac output syndrome (LCOS) is a serious complication after cardiac surgery. Despite scientific interest in LCOS, there is no uniform definition used in current research and clinicians cannot properly compare different study findings. We aimed to collect the LCOS definitions used in...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.926957/full |
| _version_ | 1811206787995533312 |
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| author | Anna Schoonen Wilton A. van Klei Wilton A. van Klei Wilton A. van Klei Wilton A. van Klei Leo van Wolfswinkel Kim van Loon |
| author_facet | Anna Schoonen Wilton A. van Klei Wilton A. van Klei Wilton A. van Klei Wilton A. van Klei Leo van Wolfswinkel Kim van Loon |
| author_sort | Anna Schoonen |
| collection | DOAJ |
| description | ObjectivesLow cardiac output syndrome (LCOS) is a serious complication after cardiac surgery. Despite scientific interest in LCOS, there is no uniform definition used in current research and clinicians cannot properly compare different study findings. We aimed to collect the LCOS definitions used in literature and subsequently applied the definitions obtained to existing data to estimate their effect on the intraoperative LCOS incidences in adults, children and infants.DesignThis is a literature review, followed by a retrospective cohort study.SettingThis is a single-institutional study from a university hospital in the Netherlands.ParticipantsPatients from all ages undergoing cardiac surgery with cardiopulmonary bypass between June 2011 and August 2018.InterventionsWe obtained different definitions of LCOS used in the literature and applied these to data obtained from an anesthesia information management system to estimate intraoperative incidences of LCOS. We compared intraoperative incidences of LCOS in different populations based on age (infants, children and adults).Measurements and main resultsThe literature search identified 262 LCOS definitions, that were applied to intraoperative data from 7,366 patients. Using the 10 most frequently published LCOS definitions, the obtained incidence estimates ranged from 0.4 to 82% in infants, from 0.6 to 56% in children and from 1.5 to 91% in adults.ConclusionThere is an important variety in definitions used to describe LCOS. When applied to data obtained from clinical care, these different definitions resulted in large distribution of intraoperative LCOS incidence rates. We therefore advocate for standardization of the LCOS definition to improve clinical understanding and enable adequate comparison of outcomes and treatment effects both in daily care and in research. |
| first_indexed | 2024-04-12T03:52:50Z |
| format | Article |
| id | doaj.art-59b31ba3a856452f9d584a078d8d6290 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-12T03:52:50Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-59b31ba3a856452f9d584a078d8d62902022-12-22T03:48:55ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-09-01910.3389/fcvm.2022.926957926957Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort studyAnna Schoonen0Wilton A. van Klei1Wilton A. van Klei2Wilton A. van Klei3Wilton A. van Klei4Leo van Wolfswinkel5Kim van Loon6Department of Anesthesiology, University Medical Center Utrecht, Utrecht, NetherlandsDepartment of Anesthesiology, University Medical Center Utrecht, Utrecht, NetherlandsDepartment of Anesthesia and Pain Management Toronto General Hospital, University Health Network, Toronto, ON, CanadaDepartment of Anesthesiology and Pain Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, CanadaToronto General Hospital Research Institute, Toronto General Hospital, Toronto, ON, CanadaDepartment of Anesthesiology, University Medical Center Utrecht, Utrecht, NetherlandsDepartment of Anesthesiology, University Medical Center Utrecht, Utrecht, NetherlandsObjectivesLow cardiac output syndrome (LCOS) is a serious complication after cardiac surgery. Despite scientific interest in LCOS, there is no uniform definition used in current research and clinicians cannot properly compare different study findings. We aimed to collect the LCOS definitions used in literature and subsequently applied the definitions obtained to existing data to estimate their effect on the intraoperative LCOS incidences in adults, children and infants.DesignThis is a literature review, followed by a retrospective cohort study.SettingThis is a single-institutional study from a university hospital in the Netherlands.ParticipantsPatients from all ages undergoing cardiac surgery with cardiopulmonary bypass between June 2011 and August 2018.InterventionsWe obtained different definitions of LCOS used in the literature and applied these to data obtained from an anesthesia information management system to estimate intraoperative incidences of LCOS. We compared intraoperative incidences of LCOS in different populations based on age (infants, children and adults).Measurements and main resultsThe literature search identified 262 LCOS definitions, that were applied to intraoperative data from 7,366 patients. Using the 10 most frequently published LCOS definitions, the obtained incidence estimates ranged from 0.4 to 82% in infants, from 0.6 to 56% in children and from 1.5 to 91% in adults.ConclusionThere is an important variety in definitions used to describe LCOS. When applied to data obtained from clinical care, these different definitions resulted in large distribution of intraoperative LCOS incidence rates. We therefore advocate for standardization of the LCOS definition to improve clinical understanding and enable adequate comparison of outcomes and treatment effects both in daily care and in research.https://www.frontiersin.org/articles/10.3389/fcvm.2022.926957/fulllow cardiac output syndromecomplicationdefinitionsincidencecardiac surgeryLCOS |
| spellingShingle | Anna Schoonen Wilton A. van Klei Wilton A. van Klei Wilton A. van Klei Wilton A. van Klei Leo van Wolfswinkel Kim van Loon Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort study Frontiers in Cardiovascular Medicine low cardiac output syndrome complication definitions incidence cardiac surgery LCOS |
| title | Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort study |
| title_full | Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort study |
| title_fullStr | Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort study |
| title_full_unstemmed | Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort study |
| title_short | Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS: A literature review and cohort study |
| title_sort | definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative lcos a literature review and cohort study |
| topic | low cardiac output syndrome complication definitions incidence cardiac surgery LCOS |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.926957/full |
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