Isoflurane exposure in infant rats acutely increases aquaporin 4 and does not cause neurocognitive impairment

Isoflurane exposure in infant rats acutely increases aquaporin 4 and does not cause neurocognitive impairment

Isoflurane is commonly used in pediatric population, but its mechanism of action in cognition is unclear. Aquaporin 4 (AQP4) regulates water content in blood, brain, and cerebrospinal fluid. Various studies have provided evidence for the role of AQP4 in synaptic plasticity and neurocognition. In th...

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Bibliographic Details
Main Authors: Serdar Demirgan, Onat Akyol, Zeynep Temel, Aslıhan Şengelen, Murat Pekmez, Recep Demirgan, Mehmet Salih Sevdi, Kerem Erkalp, Ayşin Selcan
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2019-08-01
Series:Biomolecules & Biomedicine
Subjects:
Anesthesia
aquaporin 4 (AQP4)
neurocognition
infant rat
isoflurane
pediatric anesthesia
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/4116

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