Intensive care unit bugs in India: How do they differ from the western world?

Infections continue to play a significant role in the overall global mortality and disability more so in Intensive Care Units (ICUs) and plague developing countries more intensively. The ICUs are often called “the hubs” of infections owing to highly vulnerable patients’ profile. The most important n...

Full description

Bibliographic Details
Main Authors: Dhruva Chaudhry, Brijesh Prajapat
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:The Journal of Association of Chest Physicians
Subjects:
Online Access:http://www.jacpjournal.org/article.asp?issn=2320-8775;year=2017;volume=5;issue=1;spage=10;epage=17;aulast=Chaudhry
Description
Summary:Infections continue to play a significant role in the overall global mortality and disability more so in Intensive Care Units (ICUs) and plague developing countries more intensively. The ICUs are often called “the hubs” of infections owing to highly vulnerable patients’ profile. The most important nosocomial infections in the ICU are catheter-related bloodstream infections, ventilator-associated pneumonia, and catheter-associated urinary tract infections. The epidemiology of ICU infections in India is different from its Western counterparts in terms of prevalence and nature of microorganisms causing it. While Gram-positive infections are more prevalent in Western ICUs, Indian ICUs are commonly afflicted with Gram-negative bugs showing a high degree of antimicrobial resistance with blurring of traditional boundaries of early drug sensitive and later drug resistance infections. Increasing number of multidrug resistance organism infections in ICUs is a big public health threat and challenge both from the perspective of prevention and treatment. Therefore, blindly following the Western guidelines may not provide the optimum results in India. The need of the hour is to develop and implement an antimicrobial stewardship program based on the local epidemiological data and international guidelines to optimize the antimicrobial use among the hospitalized patients and improve their outcomes.
ISSN:2320-8775
2320-9089