Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics?
New technological progress and increased demands for fish as a source of animal protein are driving significant growth of aquaculture production. Intensification of production increases the severity and frequency of infectious disease outbreaks, and so requires significant effort to prevent...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Faculty of Veterinary Medicine, Belgrade
2022-01-01
|
| Series: | Veterinarski Glasnik |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0350-2457/2022/0350-24572202091P.pdf |
| _version_ | 1827993673056387072 |
|---|---|
| author | Palić Dušan Aksentijević Ksenija |
| author_facet | Palić Dušan Aksentijević Ksenija |
| author_sort | Palić Dušan |
| collection | DOAJ |
| description | New technological progress and increased demands for fish as a source of
animal protein are driving significant growth of aquaculture production.
Intensification of production increases the severity and frequency of
infectious disease outbreaks, and so requires significant effort to prevent
and control disease. Because of the global crisis of bacterial resistance to
antibiotics, the use of antibiotics in aquaculture is increasingly subjected
to strict control and regulatory measures, leading to potential misuse. The
lack of availability of approved veterinary medical products for use in
aquaculture, combined with the risk of drug resistance development and
antibiotic residues in fish flesh or water, support the development of
preventive actions, including vaccines. However, the diversity of species
and aquaculture production methods, including epidemiological units and
their links, results in economic challenges for commercial vaccine
development and authorization. As a possible response to the increasing
demand for less antibiotic use in fish farms, and to the expenses associated
with novel veterinary product development, there is a need for increased use
of safe and effective autogenous vaccines in aquaculture. Regulatory
processes for autogenous vaccine production, approval and application should
recognize the specificities of epidemiological units and their links in
aquatic animal production facilities. The joint efforts of regulatory
authorities, producers, and veterinary services to follow veterinary
biosecurity principles, including risk analysis, surveillance, and
selection/prioritization of pathogens, are essential to provide maximum
safety and efficacy of autogenous vaccines as disease prevention and control
tools within larger areas, such as compartments and zones, and allow for
reductions in antibiotic use. |
| first_indexed | 2024-04-10T04:29:26Z |
| format | Article |
| id | doaj.art-59b6da47bcda4f6e97c02bbee939f80c |
| institution | Directory Open Access Journal |
| issn | 0350-2457 2406-0771 |
| language | English |
| last_indexed | 2024-04-10T04:29:26Z |
| publishDate | 2022-01-01 |
| publisher | Faculty of Veterinary Medicine, Belgrade |
| record_format | Article |
| series | Veterinarski Glasnik |
| spelling | doaj.art-59b6da47bcda4f6e97c02bbee939f80c2023-03-10T08:07:41ZengFaculty of Veterinary Medicine, BelgradeVeterinarski Glasnik0350-24572406-07712022-01-017629110210.2298/VETGL220926016P0350-24572202091PAutogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics?Palić Dušan0Aksentijević Ksenija1https://orcid.org/0000-0003-2546-8366University of Munich, Faculty of Veterinary Medicine, Ludwig-Maximilians, Chair for Fish Diseases and Fisheries Biology, Munich, GermanyUniversity of Belgrade, Faculty of Veterinary Medicine, Department of Microbiology - Fish Diseases, Belgrade, SerbiaNew technological progress and increased demands for fish as a source of animal protein are driving significant growth of aquaculture production. Intensification of production increases the severity and frequency of infectious disease outbreaks, and so requires significant effort to prevent and control disease. Because of the global crisis of bacterial resistance to antibiotics, the use of antibiotics in aquaculture is increasingly subjected to strict control and regulatory measures, leading to potential misuse. The lack of availability of approved veterinary medical products for use in aquaculture, combined with the risk of drug resistance development and antibiotic residues in fish flesh or water, support the development of preventive actions, including vaccines. However, the diversity of species and aquaculture production methods, including epidemiological units and their links, results in economic challenges for commercial vaccine development and authorization. As a possible response to the increasing demand for less antibiotic use in fish farms, and to the expenses associated with novel veterinary product development, there is a need for increased use of safe and effective autogenous vaccines in aquaculture. Regulatory processes for autogenous vaccine production, approval and application should recognize the specificities of epidemiological units and their links in aquatic animal production facilities. The joint efforts of regulatory authorities, producers, and veterinary services to follow veterinary biosecurity principles, including risk analysis, surveillance, and selection/prioritization of pathogens, are essential to provide maximum safety and efficacy of autogenous vaccines as disease prevention and control tools within larger areas, such as compartments and zones, and allow for reductions in antibiotic use.http://www.doiserbia.nb.rs/img/doi/0350-2457/2022/0350-24572202091P.pdfautogenous vaccineantibiotic resistant bacteriaantibiotic resistanceaquacultureveterinary service |
| spellingShingle | Palić Dušan Aksentijević Ksenija Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics? Veterinarski Glasnik autogenous vaccine antibiotic resistant bacteria antibiotic resistance aquaculture veterinary service |
| title | Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics? |
| title_full | Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics? |
| title_fullStr | Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics? |
| title_full_unstemmed | Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics? |
| title_short | Autogenous vaccines in aquaculture: Tool to combat resistance of bacteria to antibiotics? |
| title_sort | autogenous vaccines in aquaculture tool to combat resistance of bacteria to antibiotics |
| topic | autogenous vaccine antibiotic resistant bacteria antibiotic resistance aquaculture veterinary service |
| url | http://www.doiserbia.nb.rs/img/doi/0350-2457/2022/0350-24572202091P.pdf |
| work_keys_str_mv | AT palicdusan autogenousvaccinesinaquaculturetooltocombatresistanceofbacteriatoantibiotics AT aksentijevicksenija autogenousvaccinesinaquaculturetooltocombatresistanceofbacteriatoantibiotics |