Takotsubo syndrome
Takotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium. Coronary angiography...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-01-01
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| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483217301967 |
| _version_ | 1819094853977374720 |
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| author | Sanjiv Gupta Madan Mohan Gupta |
| author_facet | Sanjiv Gupta Madan Mohan Gupta |
| author_sort | Sanjiv Gupta |
| collection | DOAJ |
| description | Takotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium. Coronary angiography reveals normal epicardial arteries with no obstruction or spasm. NT-ProBNP maybe remarkably elevated. Regional wall motion akinesia (RWMA) of left ventricle extends beyond the territory of one coronary artery. Reduced left ventricle ejection fraction (LVEF) and RWMA recover in 6–12 weeks. Prognosis is generally good. Recent meta-analysis shows in-hospital mortality of 1–4.5% and recurrence rate of 5–10% during five year follow-up. |
| first_indexed | 2024-12-21T23:34:01Z |
| format | Article |
| id | doaj.art-59bc8554816e4dca8a81e862632be122 |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-21T23:34:01Z |
| publishDate | 2018-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-59bc8554816e4dca8a81e862632be1222022-12-21T18:46:24ZengElsevierIndian Heart Journal0019-48322018-01-0170116517410.1016/j.ihj.2017.09.005Takotsubo syndromeSanjiv Gupta0Madan Mohan Gupta1NH Narayana Multispeciality Hospital, Jaipur, IndiaHeart and Diabetic Clinic, B-19, Rajender Marg, Bapu Nagar, Jaipur, IndiaTakotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium. Coronary angiography reveals normal epicardial arteries with no obstruction or spasm. NT-ProBNP maybe remarkably elevated. Regional wall motion akinesia (RWMA) of left ventricle extends beyond the territory of one coronary artery. Reduced left ventricle ejection fraction (LVEF) and RWMA recover in 6–12 weeks. Prognosis is generally good. Recent meta-analysis shows in-hospital mortality of 1–4.5% and recurrence rate of 5–10% during five year follow-up.http://www.sciencedirect.com/science/article/pii/S0019483217301967Left ventricular failure (LVF)Regional wall motion abnormalities (RWMA)Apical ballooning syndrome |
| spellingShingle | Sanjiv Gupta Madan Mohan Gupta Takotsubo syndrome Indian Heart Journal Left ventricular failure (LVF) Regional wall motion abnormalities (RWMA) Apical ballooning syndrome |
| title | Takotsubo syndrome |
| title_full | Takotsubo syndrome |
| title_fullStr | Takotsubo syndrome |
| title_full_unstemmed | Takotsubo syndrome |
| title_short | Takotsubo syndrome |
| title_sort | takotsubo syndrome |
| topic | Left ventricular failure (LVF) Regional wall motion abnormalities (RWMA) Apical ballooning syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S0019483217301967 |
| work_keys_str_mv | AT sanjivgupta takotsubosyndrome AT madanmohangupta takotsubosyndrome |