In vivo pharmacokinetic/Pharmacodynamic modeling of Enrofloxacin against Escherichia coli in broiler chickens

In vivo pharmacokinetic/Pharmacodynamic modeling of Enrofloxacin against Escherichia coli in broiler chickens

Abstract Background Systemic Escherichia coli infections cause early mortality of commercial broiler chickens. Although enrofloxacin has long been used in poultry, the in vivo pharmacokinetic/pharmacodynamic (PK/PD) relationship of enrofloxacin against E. coli is unclear. The present study aimed to...

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Bibliographic Details
Main Authors: Xia Xiao, Lijie Jiang, Weixuan Lan, Yongjia Jiang, Zhiqiang Wang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Veterinary Research
Subjects:
Escherichia coli
Enrofloxacin
In vivo
PK/PD modeling
Chicken
Online Access:http://link.springer.com/article/10.1186/s12917-018-1698-3

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