Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction.

Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction.

OBJECTIVE: Autophagy is activated in ischemic heart diseases, but its dynamics and functional roles remain unclear and controversial. In this study, we investigated the dynamics and role of autophagy and the mechanism(s), if any, during postinfarction cardiac remodeling. METHODS AND RESULTS: Acute m...

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Bibliographic Details
Main Authors: Xiaoqian Wu, Lishan He, Fajiang Chen, Xiaoen He, Yi Cai, Guiping Zhang, Quan Yi, Meixiang He, Jiandong Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4237367?pdf=render

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