Ubiquitin Ligase Nrdp1 Controls Autophagy-Associated Acrosome Biogenesis and Mitochondrial Arrangement during Spermiogenesis

Ubiquitin Ligase Nrdp1 Controls Autophagy-Associated Acrosome Biogenesis and Mitochondrial Arrangement during Spermiogenesis

Autophagy is critical to acrosome biogenesis and mitochondrial quality control, but the underlying mechanisms remain unclear. The ubiquitin ligase Nrdp1/RNF41 promotes ubiquitination of the mitophagy-associated Parkin and interacts with the pro-autophagic protein SIP/CacyBP. Here, we report that glo...

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Bibliographic Details
Main Authors: Zi-Yu Luo, Tian-Xia Jiang, Tao Zhang, Ping Xu, Xiao-Bo Qiu
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
ubiquitin ligase
Nrdp1
Parkin
SIP/CacyBP
autophagy
acrosome
Online Access:https://www.mdpi.com/2073-4409/12/18/2211

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