Screening for Distress and Health Outcomes in Head and Neck Cancer
Head and neck cancers (HNC) have higher rates of emotional distress than other cancer types and the general population. This paper compares the prevalence of emotional distress in HNC across various distress screening measures and examines whether significant distress or distress screening are assoc...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/29/6/304 |
| _version_ | 1797488440205377536 |
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| author | Bryan Gascon Aliza A. Panjwani Olivia Mazzurco Madeline Li |
| author_facet | Bryan Gascon Aliza A. Panjwani Olivia Mazzurco Madeline Li |
| author_sort | Bryan Gascon |
| collection | DOAJ |
| description | Head and neck cancers (HNC) have higher rates of emotional distress than other cancer types and the general population. This paper compares the prevalence of emotional distress in HNC across various distress screening measures and examines whether significant distress or distress screening are associated with cancer-related survival. A retrospective observational cohort design was employed, with data collected from the Distress Assessment and Response Tool (DART) and linkages to administrative databases from 2010 to 2016. Descriptive and prevalence data were reported using multiple concurrently administered distress tools, including the Patient Health Questionaire-9 (PHQ-9), Generalized Anxiety Disorders-7 (GAD-7), Edmonton Symptom Assessment Scale-revised (ESAS-r), and MD Anderson Symptom Index-Head and Neck module (MDASI-HN). Across measures, 7.8 to 28.1% of the sample reported clinically significant emotional distress, with PHQ-9 and GAD-7 identifying lowest prevalence of moderate/severe distress, and the ultrashort distress screens within ESAS-r and MDASI-HN performing equivalently. Cox hazards models were used in univariate and multivariate survival analyses. ESAS depression (≥4), but not anxiety, was associated with increased risk of cancer-related mortality and patient completion of DART was associated with greater cancer-related survival. The findings underscore the importance of implementing routine distress screening for HNC populations and the utility of ultra-brief screening measures. |
| first_indexed | 2024-03-10T00:02:16Z |
| format | Article |
| id | doaj.art-59c13bf7b10d4b27ab7e95f1224a44e9 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-10T00:02:16Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-59c13bf7b10d4b27ab7e95f1224a44e92023-11-23T16:13:36ZengMDPI AGCurrent Oncology1198-00521718-77292022-05-012963793380610.3390/curroncol29060304Screening for Distress and Health Outcomes in Head and Neck CancerBryan Gascon0Aliza A. Panjwani1Olivia Mazzurco2Madeline Li3Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, CanadaDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, CanadaDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, CanadaTemerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, CanadaHead and neck cancers (HNC) have higher rates of emotional distress than other cancer types and the general population. This paper compares the prevalence of emotional distress in HNC across various distress screening measures and examines whether significant distress or distress screening are associated with cancer-related survival. A retrospective observational cohort design was employed, with data collected from the Distress Assessment and Response Tool (DART) and linkages to administrative databases from 2010 to 2016. Descriptive and prevalence data were reported using multiple concurrently administered distress tools, including the Patient Health Questionaire-9 (PHQ-9), Generalized Anxiety Disorders-7 (GAD-7), Edmonton Symptom Assessment Scale-revised (ESAS-r), and MD Anderson Symptom Index-Head and Neck module (MDASI-HN). Across measures, 7.8 to 28.1% of the sample reported clinically significant emotional distress, with PHQ-9 and GAD-7 identifying lowest prevalence of moderate/severe distress, and the ultrashort distress screens within ESAS-r and MDASI-HN performing equivalently. Cox hazards models were used in univariate and multivariate survival analyses. ESAS depression (≥4), but not anxiety, was associated with increased risk of cancer-related mortality and patient completion of DART was associated with greater cancer-related survival. The findings underscore the importance of implementing routine distress screening for HNC populations and the utility of ultra-brief screening measures.https://www.mdpi.com/1718-7729/29/6/304head and neck cancerdistress screeningdepressionanxietyemotional distresssurvival |
| spellingShingle | Bryan Gascon Aliza A. Panjwani Olivia Mazzurco Madeline Li Screening for Distress and Health Outcomes in Head and Neck Cancer Current Oncology head and neck cancer distress screening depression anxiety emotional distress survival |
| title | Screening for Distress and Health Outcomes in Head and Neck Cancer |
| title_full | Screening for Distress and Health Outcomes in Head and Neck Cancer |
| title_fullStr | Screening for Distress and Health Outcomes in Head and Neck Cancer |
| title_full_unstemmed | Screening for Distress and Health Outcomes in Head and Neck Cancer |
| title_short | Screening for Distress and Health Outcomes in Head and Neck Cancer |
| title_sort | screening for distress and health outcomes in head and neck cancer |
| topic | head and neck cancer distress screening depression anxiety emotional distress survival |
| url | https://www.mdpi.com/1718-7729/29/6/304 |
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