Oral delivery of Eimeria acervulina transfected sequentially with two copies of the VP2 gene induces immunity against infectious bursal disease virus in chickens

Oral delivery of Eimeria acervulina transfected sequentially with two copies of the VP2 gene induces immunity against infectious bursal disease virus in chickens

Chicken coccidiosis caused by Eimeria spp. can occur on almost all poultry farms, causing huge economic losses to the industry. Genetically manipulated Eimeria parasites as a vaccine vector to deliver viral antigens have been reported. In our preliminary study, transgenic E. acervulina expressing a...

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Bibliographic Details
Main Authors: Qingbin Guo, Ying Yu, Jingxia Suo, Xinming Tang, Sixin Zhang, Colin Crouch, Beth Bruton, Ian Tarpey, Xianyong Liu, Guanghui Zhao, Xun Suo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Veterinary Science
Subjects:
chicken
coccidia
delivery vector
genetic manipulation
viral antigen
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2024.1367912/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2024.1367912/full

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