Electrospun Polydioxanone Loaded With Chloroquine Modulates Template-Induced NET Release and Inflammatory Responses From Human Neutrophils

Electrospun Polydioxanone Loaded With Chloroquine Modulates Template-Induced NET Release and Inflammatory Responses From Human Neutrophils

The implantation of a biomaterial quickly initiates a tissue repair program initially characterized by a neutrophil influx. During the acute inflammatory response, neutrophils release neutrophil extracellular traps (NETs) and secrete soluble signals to modulate the tissue environment. In this work,...

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Bibliographic Details
Main Authors: Allison E. Fetz, Shannon E. Wallace, Gary L. Bowlin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
tissue regeneration
electrospinning
tissue engineering
neutrophils
neutrophil extracellular traps
NETs
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.652055/full

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