Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases
Currently, there is enough data to suggest a significant role of microcirculation abnormalities in the pathophysiology of COVID-19. However, no clinical studies on noninvasive assessment of blood microcirculation in patients with the new coronavirus infection have been performed. We measured skin mi...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
MONIKI
2020-09-01
|
Series: | Alʹmanah Kliničeskoj Mediciny |
Subjects: | |
Online Access: | https://www.almclinmed.ru/jour/article/view/1345 |
_version_ | 1818642350624210944 |
---|---|
author | P. A. Glazkova D. A. Kulikov D. A. Rogatkin O. R. Zhuravlev G. G. Shekhyan А. A. Glazkov K. A. Kozlova S. A. Terpigorev |
author_facet | P. A. Glazkova D. A. Kulikov D. A. Rogatkin O. R. Zhuravlev G. G. Shekhyan А. A. Glazkov K. A. Kozlova S. A. Terpigorev |
author_sort | P. A. Glazkova |
collection | DOAJ |
description | Currently, there is enough data to suggest a significant role of microcirculation abnormalities in the pathophysiology of COVID-19. However, no clinical studies on noninvasive assessment of blood microcirculation in patients with the new coronavirus infection have been performed. We measured skin microcirculation by laser Doppler flowmetry in the thermal and inspiratory gasp tests in 3 patients with various courses of COVID-19. A decrease in the skin microcirculation reactivity was found in a patient with a more severe course of coronavirus infection. We believe that assessment of skin microcirculation could become a promising tool for the development of new diagnostic approaches and in future of new treatments for patients with coronavirus infection, as well as for identification of patient categories with a high risk of its severe course. Further studies are required to evaluate the clinical applicability of laser Doppler flowmetry for assessment of skin microcirculation in patients with COVID-19. |
first_indexed | 2024-12-16T23:41:40Z |
format | Article |
id | doaj.art-59c996fa500e41bc827b2bf779de7c4d |
institution | Directory Open Access Journal |
issn | 2072-0505 2587-9294 |
language | Russian |
last_indexed | 2024-12-16T23:41:40Z |
publishDate | 2020-09-01 |
publisher | MONIKI |
record_format | Article |
series | Alʹmanah Kliničeskoj Mediciny |
spelling | doaj.art-59c996fa500e41bc827b2bf779de7c4d2022-12-21T22:11:35ZrusMONIKIAlʹmanah Kliničeskoj Mediciny2072-05052587-92942020-09-01480273110.18786/2072-0505-2020-48-037742Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical casesP. A. Glazkova0D. A. Kulikov1D. A. Rogatkin2O. R. Zhuravlev3G. G. Shekhyan4А. A. Glazkov5K. A. Kozlova6S. A. Terpigorev7Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Currently, there is enough data to suggest a significant role of microcirculation abnormalities in the pathophysiology of COVID-19. However, no clinical studies on noninvasive assessment of blood microcirculation in patients with the new coronavirus infection have been performed. We measured skin microcirculation by laser Doppler flowmetry in the thermal and inspiratory gasp tests in 3 patients with various courses of COVID-19. A decrease in the skin microcirculation reactivity was found in a patient with a more severe course of coronavirus infection. We believe that assessment of skin microcirculation could become a promising tool for the development of new diagnostic approaches and in future of new treatments for patients with coronavirus infection, as well as for identification of patient categories with a high risk of its severe course. Further studies are required to evaluate the clinical applicability of laser Doppler flowmetry for assessment of skin microcirculation in patients with COVID-19.https://www.almclinmed.ru/jour/article/view/1345coronavirus infectionscovid-19microcirculationskinlaser doppler flowmetry |
spellingShingle | P. A. Glazkova D. A. Kulikov D. A. Rogatkin O. R. Zhuravlev G. G. Shekhyan А. A. Glazkov K. A. Kozlova S. A. Terpigorev Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases Alʹmanah Kliničeskoj Mediciny coronavirus infections covid-19 microcirculation skin laser doppler flowmetry |
title | Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases |
title_full | Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases |
title_fullStr | Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases |
title_full_unstemmed | Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases |
title_short | Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases |
title_sort | non invasive assessment of skin microcirculation in patients with covid 19 three clinical cases |
topic | coronavirus infections covid-19 microcirculation skin laser doppler flowmetry |
url | https://www.almclinmed.ru/jour/article/view/1345 |
work_keys_str_mv | AT paglazkova noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases AT dakulikov noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases AT darogatkin noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases AT orzhuravlev noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases AT ggshekhyan noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases AT aaglazkov noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases AT kakozlova noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases AT saterpigorev noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases |