Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases

Currently, there is enough data to suggest a significant role of microcirculation abnormalities in the pathophysiology of COVID-19. However, no clinical studies on noninvasive assessment of blood microcirculation in patients with the new coronavirus infection have been performed. We measured skin mi...

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Main Authors: P. A. Glazkova, D. A. Kulikov, D. A. Rogatkin, O. R. Zhuravlev, G. G. Shekhyan, А. A. Glazkov, K. A. Kozlova, S. A. Terpigorev
Format: Article
Language:Russian
Published: MONIKI 2020-09-01
Series:Alʹmanah Kliničeskoj Mediciny
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Online Access:https://www.almclinmed.ru/jour/article/view/1345
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author P. A. Glazkova
D. A. Kulikov
D. A. Rogatkin
O. R. Zhuravlev
G. G. Shekhyan
А. A. Glazkov
K. A. Kozlova
S. A. Terpigorev
author_facet P. A. Glazkova
D. A. Kulikov
D. A. Rogatkin
O. R. Zhuravlev
G. G. Shekhyan
А. A. Glazkov
K. A. Kozlova
S. A. Terpigorev
author_sort P. A. Glazkova
collection DOAJ
description Currently, there is enough data to suggest a significant role of microcirculation abnormalities in the pathophysiology of COVID-19. However, no clinical studies on noninvasive assessment of blood microcirculation in patients with the new coronavirus infection have been performed. We measured skin microcirculation by laser Doppler flowmetry in the thermal and inspiratory gasp tests in 3 patients with various courses of COVID-19. A decrease in the skin microcirculation reactivity was found in a patient with a more severe course of coronavirus infection. We believe that assessment of skin microcirculation could become a promising tool for the development of new diagnostic approaches and in future of new treatments for patients with coronavirus infection, as well as for identification of patient categories with a high risk of its severe course. Further studies are required to evaluate the clinical applicability of laser Doppler flowmetry for assessment of skin microcirculation in patients with COVID-19.
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spelling doaj.art-59c996fa500e41bc827b2bf779de7c4d2022-12-21T22:11:35ZrusMONIKIAlʹmanah Kliničeskoj Mediciny2072-05052587-92942020-09-01480273110.18786/2072-0505-2020-48-037742Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical casesP. A. Glazkova0D. A. Kulikov1D. A. Rogatkin2O. R. Zhuravlev3G. G. Shekhyan4А. A. Glazkov5K. A. Kozlova6S. A. Terpigorev7Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Moscow Regional Research and Clinical Institute (MONIKI)Currently, there is enough data to suggest a significant role of microcirculation abnormalities in the pathophysiology of COVID-19. However, no clinical studies on noninvasive assessment of blood microcirculation in patients with the new coronavirus infection have been performed. We measured skin microcirculation by laser Doppler flowmetry in the thermal and inspiratory gasp tests in 3 patients with various courses of COVID-19. A decrease in the skin microcirculation reactivity was found in a patient with a more severe course of coronavirus infection. We believe that assessment of skin microcirculation could become a promising tool for the development of new diagnostic approaches and in future of new treatments for patients with coronavirus infection, as well as for identification of patient categories with a high risk of its severe course. Further studies are required to evaluate the clinical applicability of laser Doppler flowmetry for assessment of skin microcirculation in patients with COVID-19.https://www.almclinmed.ru/jour/article/view/1345coronavirus infectionscovid-19microcirculationskinlaser doppler flowmetry
spellingShingle P. A. Glazkova
D. A. Kulikov
D. A. Rogatkin
O. R. Zhuravlev
G. G. Shekhyan
А. A. Glazkov
K. A. Kozlova
S. A. Terpigorev
Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases
Alʹmanah Kliničeskoj Mediciny
coronavirus infections
covid-19
microcirculation
skin
laser doppler flowmetry
title Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases
title_full Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases
title_fullStr Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases
title_full_unstemmed Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases
title_short Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases
title_sort non invasive assessment of skin microcirculation in patients with covid 19 three clinical cases
topic coronavirus infections
covid-19
microcirculation
skin
laser doppler flowmetry
url https://www.almclinmed.ru/jour/article/view/1345
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AT orzhuravlev noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases
AT ggshekhyan noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases
AT aaglazkov noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases
AT kakozlova noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases
AT saterpigorev noninvasiveassessmentofskinmicrocirculationinpatientswithcovid19threeclinicalcases