Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaption
Magnetic resonance-guided radiotherapy with daily plan adaptation for intermediate- and high-risk prostate cancer is time and labor intensive. Fifty adapted plans with 3 mm planning target volume (PTV)-margin were compared with non-adapted plans using 3 or 5 mm margins. Adequate (V95% ≥ 95%) prostat...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-07-01
|
| Series: | Physics and Imaging in Radiation Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405631622000616 |
| _version_ | 1828408711151878144 |
|---|---|
| author | Shyama U. Tetar Anna M.E. Bruynzeel Lisa Verweij Omar Bohoudi Berend J. Slotman Tezontl Rosario Miguel A. Palacios Frank J. Lagerwaard |
| author_facet | Shyama U. Tetar Anna M.E. Bruynzeel Lisa Verweij Omar Bohoudi Berend J. Slotman Tezontl Rosario Miguel A. Palacios Frank J. Lagerwaard |
| author_sort | Shyama U. Tetar |
| collection | DOAJ |
| description | Magnetic resonance-guided radiotherapy with daily plan adaptation for intermediate- and high-risk prostate cancer is time and labor intensive. Fifty adapted plans with 3 mm planning target volume (PTV)-margin were compared with non-adapted plans using 3 or 5 mm margins. Adequate (V95% ≥ 95%) prostate coverage was achieved in 49 fractions with 5 mm PTV without plan adaptation, however, coverage of the seminal vesicles (SV) was insufficient in 15 of 50 fractions. There was no insufficient coverage for prostate and SV using plan adaptation with 3 mm. Hence, daily adaptation is recommended to obtain adequate SV-coverage when using 3 mm PTV. |
| first_indexed | 2024-12-10T11:42:47Z |
| format | Article |
| id | doaj.art-59caafc3f34d4dc28ac77cecf5f3f592 |
| institution | Directory Open Access Journal |
| issn | 2405-6316 |
| language | English |
| last_indexed | 2024-12-10T11:42:47Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Physics and Imaging in Radiation Oncology |
| spelling | doaj.art-59caafc3f34d4dc28ac77cecf5f3f5922022-12-22T01:50:11ZengElsevierPhysics and Imaging in Radiation Oncology2405-63162022-07-01239296Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaptionShyama U. Tetar0Anna M.E. Bruynzeel1Lisa Verweij2Omar Bohoudi3Berend J. Slotman4Tezontl Rosario5Miguel A. Palacios6Frank J. Lagerwaard7Department of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, de Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsDepartment of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, de Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsDepartment of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, de Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsDepartment of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, de Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsDepartment of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, de Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsDepartment of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, de Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsDepartment of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, de Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsCorresponding author at: Amsterdam UMC, location VUmc, Postbox 7057, 1007 MB Amsterdam, The Netherlands.; Department of Radiation Oncology, Amsterdam University Medical Centers, Location VUmc, de Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsMagnetic resonance-guided radiotherapy with daily plan adaptation for intermediate- and high-risk prostate cancer is time and labor intensive. Fifty adapted plans with 3 mm planning target volume (PTV)-margin were compared with non-adapted plans using 3 or 5 mm margins. Adequate (V95% ≥ 95%) prostate coverage was achieved in 49 fractions with 5 mm PTV without plan adaptation, however, coverage of the seminal vesicles (SV) was insufficient in 15 of 50 fractions. There was no insufficient coverage for prostate and SV using plan adaptation with 3 mm. Hence, daily adaptation is recommended to obtain adequate SV-coverage when using 3 mm PTV.http://www.sciencedirect.com/science/article/pii/S2405631622000616Prostate cancerSeminal vesiclesMR-guided radiotherapyInterfraction motionPlan adaptationDosimetry |
| spellingShingle | Shyama U. Tetar Anna M.E. Bruynzeel Lisa Verweij Omar Bohoudi Berend J. Slotman Tezontl Rosario Miguel A. Palacios Frank J. Lagerwaard Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaption Physics and Imaging in Radiation Oncology Prostate cancer Seminal vesicles MR-guided radiotherapy Interfraction motion Plan adaptation Dosimetry |
| title | Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaption |
| title_full | Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaption |
| title_fullStr | Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaption |
| title_full_unstemmed | Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaption |
| title_short | Magnetic resonance imaging-guided radiotherapy for intermediate- and high-risk prostate cancer: Trade-off between planning target volume margin and online plan adaption |
| title_sort | magnetic resonance imaging guided radiotherapy for intermediate and high risk prostate cancer trade off between planning target volume margin and online plan adaption |
| topic | Prostate cancer Seminal vesicles MR-guided radiotherapy Interfraction motion Plan adaptation Dosimetry |
| url | http://www.sciencedirect.com/science/article/pii/S2405631622000616 |
| work_keys_str_mv | AT shyamautetar magneticresonanceimagingguidedradiotherapyforintermediateandhighriskprostatecancertradeoffbetweenplanningtargetvolumemarginandonlineplanadaption AT annamebruynzeel magneticresonanceimagingguidedradiotherapyforintermediateandhighriskprostatecancertradeoffbetweenplanningtargetvolumemarginandonlineplanadaption AT lisaverweij magneticresonanceimagingguidedradiotherapyforintermediateandhighriskprostatecancertradeoffbetweenplanningtargetvolumemarginandonlineplanadaption AT omarbohoudi magneticresonanceimagingguidedradiotherapyforintermediateandhighriskprostatecancertradeoffbetweenplanningtargetvolumemarginandonlineplanadaption AT berendjslotman magneticresonanceimagingguidedradiotherapyforintermediateandhighriskprostatecancertradeoffbetweenplanningtargetvolumemarginandonlineplanadaption AT tezontlrosario magneticresonanceimagingguidedradiotherapyforintermediateandhighriskprostatecancertradeoffbetweenplanningtargetvolumemarginandonlineplanadaption AT miguelapalacios magneticresonanceimagingguidedradiotherapyforintermediateandhighriskprostatecancertradeoffbetweenplanningtargetvolumemarginandonlineplanadaption AT frankjlagerwaard magneticresonanceimagingguidedradiotherapyforintermediateandhighriskprostatecancertradeoffbetweenplanningtargetvolumemarginandonlineplanadaption |