PclR is a transcriptional activator of the gene that encodes the pneumococcal collagen-like protein PclA

Abstract The Gram-positive bacterium Streptococcus pneumoniae is a major human pathogen that shows high levels of genetic variability. The pneumococcal R6 genome harbours several gene clusters that are not present in all strains of the species. One of these clusters contains two divergent genes, pcl...

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Bibliographic Details
Main Authors: Ana Moreno-Blanco, Virtu Solano-Collado, Alejandro Ortuno-Camuñas, Manuel Espinosa, Sofía Ruiz-Cruz, Alicia Bravo
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15758-7