Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus

Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus

Cone snails produce a fast-acting and often paralyzing venom that is usually injected into their prey or predator through a hypodermic needle-like modified radula tooth. Many diverse compounds are found in their venom including small molecules, peptides and enzymes. However, peptidic toxins called c...

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Bibliographic Details
Main Authors: Julien Giribaldi, David Wilson, Annette Nicke, Yamina El Hamdaoui, Guillaume Laconde, Adèle Faucherre, Hamid Moha Ou Maati, Norelle L. Daly, Christine Enjalbal, Sébastien Dutertre
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Toxins
Subjects:
conotoxins
Conus catus
electrophysiology
in vivo
nicotinic receptors
structure
synthesis
Online Access:http://www.mdpi.com/2072-6651/10/6/222

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