The efficacy of clonidine on intraoperative bleeding in middle ear microsurgery
Introduction: The aim of this study was to evaluate the efficacy of clonidine on intraoperative bleeding in middle ear microsurgery. Materials and Methods: This prospective double-blinded clinical trial was performed on 51 patients (ASA I, II), aged 15-60 year undergoing middle ear microsurgery. The...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2010-06-01
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| Series: | Iranian Journal of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://ijorl.mums.ac.ir/?_action=showPDF&article=400&_ob=849b4f46f553d51580398e7803e5dc79&fileName=full_text.pdf |
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| author | Arash Jafariye Fatemeh Hajimohammadi Afshar Etemadi Al-e-Agha Azadeh Salavatipour Mohsen Rajati Haghi |
| author_facet | Arash Jafariye Fatemeh Hajimohammadi Afshar Etemadi Al-e-Agha Azadeh Salavatipour Mohsen Rajati Haghi |
| author_sort | Arash Jafariye |
| collection | DOAJ |
| description | Introduction: The aim of this study was to evaluate the efficacy of clonidine on intraoperative bleeding in middle ear microsurgery. Materials and Methods: This prospective double-blinded clinical trial was performed on 51 patients (ASA I, II), aged 15-60 year undergoing middle ear microsurgery. They were randomly assigned to receive either 200 micrograms clonidine per oral or placebo 90 minutes prior the operation in a double blind condition. Intraoperative bleeding was assessed on a four-point scale. Systemic blood pressure and heart rate were measured before and during surgery. Intraoperative bleeding, antihypertensive requirements, cardiovascular changes after intubation, post operative bleeding and reoperations were compared between two groups. Results: Clonidine group had a better bloodless surgical field than placebo group (P |
| first_indexed | 2024-12-11T06:11:42Z |
| format | Article |
| id | doaj.art-59d59b3be4e9492e9d2c8f2c1a57a7b9 |
| institution | Directory Open Access Journal |
| issn | 2251-7251 2251-726X |
| language | English |
| last_indexed | 2024-12-11T06:11:42Z |
| publishDate | 2010-06-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Otorhinolaryngology |
| spelling | doaj.art-59d59b3be4e9492e9d2c8f2c1a57a7b92022-12-22T01:18:06ZengMashhad University of Medical SciencesIranian Journal of Otorhinolaryngology2251-72512251-726X2010-06-01225758121126The efficacy of clonidine on intraoperative bleeding in middle ear microsurgeryArash JafariyeFatemeh HajimohammadiAfshar Etemadi Al-e-AghaAzadeh SalavatipourMohsen Rajati HaghiIntroduction: The aim of this study was to evaluate the efficacy of clonidine on intraoperative bleeding in middle ear microsurgery. Materials and Methods: This prospective double-blinded clinical trial was performed on 51 patients (ASA I, II), aged 15-60 year undergoing middle ear microsurgery. They were randomly assigned to receive either 200 micrograms clonidine per oral or placebo 90 minutes prior the operation in a double blind condition. Intraoperative bleeding was assessed on a four-point scale. Systemic blood pressure and heart rate were measured before and during surgery. Intraoperative bleeding, antihypertensive requirements, cardiovascular changes after intubation, post operative bleeding and reoperations were compared between two groups. Results: Clonidine group had a better bloodless surgical field than placebo group (Phttp://ijorl.mums.ac.ir/?_action=showPDF&article=400&_ob=849b4f46f553d51580398e7803e5dc79&fileName=full_text.pdfBleedingClonidineMicrosurgery |
| spellingShingle | Arash Jafariye Fatemeh Hajimohammadi Afshar Etemadi Al-e-Agha Azadeh Salavatipour Mohsen Rajati Haghi The efficacy of clonidine on intraoperative bleeding in middle ear microsurgery Iranian Journal of Otorhinolaryngology Bleeding Clonidine Microsurgery |
| title | The efficacy of clonidine on intraoperative bleeding in middle ear microsurgery |
| title_full | The efficacy of clonidine on intraoperative bleeding in middle ear microsurgery |
| title_fullStr | The efficacy of clonidine on intraoperative bleeding in middle ear microsurgery |
| title_full_unstemmed | The efficacy of clonidine on intraoperative bleeding in middle ear microsurgery |
| title_short | The efficacy of clonidine on intraoperative bleeding in middle ear microsurgery |
| title_sort | efficacy of clonidine on intraoperative bleeding in middle ear microsurgery |
| topic | Bleeding Clonidine Microsurgery |
| url | http://ijorl.mums.ac.ir/?_action=showPDF&article=400&_ob=849b4f46f553d51580398e7803e5dc79&fileName=full_text.pdf |
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