BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth

BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth

Summary: Clinical evidence points to a function for B cell-activating factor (BAFF) in pregnancy. However, direct roles for BAFF-axis members in pregnancy have not been examined. Here, via utility of genetically modified mice, we report that BAFF promotes inflammatory responsiveness and increases su...

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Bibliographic Details
Main Authors: Jessica R. Doll, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Jennifer L. Wayland, Adrienne Wilburn, Benjamin Weinhaus, Claire A. Chougnet, Daniela Giordano, Monica Cappelletti, Pietro Presicce, Suhas G. Kallapur, Nathan Salomonis, Tamara Tilburgs, Senad Divanovic
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003637

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