MicroRNA miR-214-5p induces senescence of microvascular endothelial cells by targeting the JAG1/Notch signaling pathway

MicroRNA miR-214-5p induces senescence of microvascular endothelial cells by targeting the JAG1/Notch signaling pathway

During cellular senescence, irreversible cell cycle arrest is accompanied by morphological and genetic alterations. MicroRNAs (miRNAs) play a critical role in regulating senescence by modulating the abundance of crucial senescence regulatory proteins. Therefore, to identify novel senescence-associat...

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Bibliographic Details
Main Authors: Hye-ram Jo, Jiwon Hwang, Jae-Hoon Jeong
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Non-coding RNA Research
Subjects:
microRNA
miR-214-5p
Senescence
Microvascular endothelial cell
Notch signaling
Jagged1
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054023000276

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