The MAPK/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes
JC polyomavirus (JCPyV) is a neuroinvasive pathogen causing a fatal, demyelinating disease of the central nervous system (CNS) known as progressive multifocal leukoencephalopathy (PML). Within the CNS, JCPyV predominately targets two cell types: oligodendrocytes and astrocytes. The underlying mechan...
Main Authors: | Michael P. Wilczek, Francesca J. Armstrong, Remi P. Geohegan, Colleen L. Mayberry, Jeanne K. DuShane, Benjamin L. King, Melissa S. Maginnis |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/13/9/1834 |
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