PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUZ) DALAM MENGHAMBAT DEGRANULASI SEL MAST DAN MENCIT PUTIH JANTAN YANG TERSENSITISASI AKTIF
Type I hypersensitivity reactions, also known as allergic reactions or anaphylactic reactions. The mechanism of anaphylaxis involves the release of mediators from mediator cells. The degranulation of mast cells and basophils causes an exaggerated immune response and causes the signs and symptoms of...
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| Format: | Artikel |
| Sprache: | English |
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Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
2023-03-01
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| Schriftenreihe: | JIIS: Jurnal Ilmiah Ibnu Sina |
| Schlagworte: | |
| Online Zugang: | https://e-jurnal.stikes-isfi.ac.id/index.php/JIIS/article/view/1061 |
| _version_ | 1827357119988367360 |
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| author | Relin Yesika Meiridha Mutiara A. |
| author_facet | Relin Yesika Meiridha Mutiara A. |
| author_sort | Relin Yesika |
| collection | DOAJ |
| description |
Type I hypersensitivity reactions, also known as allergic reactions or anaphylactic reactions. The mechanism of anaphylaxis involves the release of mediators from mediator cells. The degranulation of mast cells and basophils causes an exaggerated immune response and causes the signs and symptoms of anaphylaxis. Red dragon fruit peel contains secondary metabolites such as triterpenoid flavonoids and steroids. This study was an in vitro study of the ethanol extract of red dragon fruit peel (Hylocereus polyrhizuz) on the mast cells of male white mice induced by antigen. Five variations of the concentration used are 25; 50;100;200;400µg/mL. The percentage of mast cell degranulation by red dragon fruit peel extract at concentrations of 25;50;100;200 dan 400 µg/mL is 75.27; 69.05; 64.04, 56.61; 45.17; dan 27.88%. There Red dragon fruit peel extract had a significant effect in inhibiting mast cell degranulation (p<0.05).
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| first_indexed | 2024-03-08T05:20:53Z |
| format | Article |
| id | doaj.art-59e9fd270e7f46fa9dff80c02eda2654 |
| institution | Directory Open Access Journal |
| issn | 2502-647X 2503-1902 |
| language | English |
| last_indexed | 2024-03-08T05:20:53Z |
| publishDate | 2023-03-01 |
| publisher | Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin |
| record_format | Article |
| series | JIIS: Jurnal Ilmiah Ibnu Sina |
| spelling | doaj.art-59e9fd270e7f46fa9dff80c02eda26542024-02-06T12:54:59ZengSekolah Tinggi Ilmu Kesehatan ISFI BanjarmasinJIIS: Jurnal Ilmiah Ibnu Sina2502-647X2503-19022023-03-018110.36387/jiis.v8i1.1061PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUZ) DALAM MENGHAMBAT DEGRANULASI SEL MAST DAN MENCIT PUTIH JANTAN YANG TERSENSITISASI AKTIFRelin Yesika0Meiridha Mutiara A.1Fakultas Kedokteran, Universitas BaiturrahmahFakultas Kedokteran, Universitas Baiturrahmah Type I hypersensitivity reactions, also known as allergic reactions or anaphylactic reactions. The mechanism of anaphylaxis involves the release of mediators from mediator cells. The degranulation of mast cells and basophils causes an exaggerated immune response and causes the signs and symptoms of anaphylaxis. Red dragon fruit peel contains secondary metabolites such as triterpenoid flavonoids and steroids. This study was an in vitro study of the ethanol extract of red dragon fruit peel (Hylocereus polyrhizuz) on the mast cells of male white mice induced by antigen. Five variations of the concentration used are 25; 50;100;200;400µg/mL. The percentage of mast cell degranulation by red dragon fruit peel extract at concentrations of 25;50;100;200 dan 400 µg/mL is 75.27; 69.05; 64.04, 56.61; 45.17; dan 27.88%. There Red dragon fruit peel extract had a significant effect in inhibiting mast cell degranulation (p<0.05). https://e-jurnal.stikes-isfi.ac.id/index.php/JIIS/article/view/1061Degranulationmast cellanaphylaxisallergytype I hypersensitivity |
| spellingShingle | Relin Yesika Meiridha Mutiara A. PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUZ) DALAM MENGHAMBAT DEGRANULASI SEL MAST DAN MENCIT PUTIH JANTAN YANG TERSENSITISASI AKTIF JIIS: Jurnal Ilmiah Ibnu Sina Degranulation mast cell anaphylaxis allergy type I hypersensitivity |
| title | PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUZ) DALAM MENGHAMBAT DEGRANULASI SEL MAST DAN MENCIT PUTIH JANTAN YANG TERSENSITISASI AKTIF |
| title_full | PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUZ) DALAM MENGHAMBAT DEGRANULASI SEL MAST DAN MENCIT PUTIH JANTAN YANG TERSENSITISASI AKTIF |
| title_fullStr | PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUZ) DALAM MENGHAMBAT DEGRANULASI SEL MAST DAN MENCIT PUTIH JANTAN YANG TERSENSITISASI AKTIF |
| title_full_unstemmed | PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUZ) DALAM MENGHAMBAT DEGRANULASI SEL MAST DAN MENCIT PUTIH JANTAN YANG TERSENSITISASI AKTIF |
| title_short | PENGARUH EKSTRAK KULIT BUAH NAGA MERAH (HYLOCEREUS POLYRHIZUZ) DALAM MENGHAMBAT DEGRANULASI SEL MAST DAN MENCIT PUTIH JANTAN YANG TERSENSITISASI AKTIF |
| title_sort | pengaruh ekstrak kulit buah naga merah hylocereus polyrhizuz dalam menghambat degranulasi sel mast dan mencit putih jantan yang tersensitisasi aktif |
| topic | Degranulation mast cell anaphylaxis allergy type I hypersensitivity |
| url | https://e-jurnal.stikes-isfi.ac.id/index.php/JIIS/article/view/1061 |
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