Glucocorticoid induced bone disorders in children: Research progress in treatment mechanisms

Glucocorticoid induced bone disorders in children: Research progress in treatment mechanisms

Long-term or supra-physiological dose of glucocorticoid (GC) application in clinic can lead to impaired bone growth and osteoporosis. The side effects of GC on the skeletal system are particularly serious in growing children, potentially causing growth retardation or even osteoporotic fractures. Chi...

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Bibliographic Details
Main Authors: Junying Hua, Jianping Huang, Gang Li, Sien Lin, Liao Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Endocrinology
Subjects:
growth hormone
growth plate
bone growth suppression
glucocorticoid (GC)
chondrocyte 3
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1119427/full

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