Environmental approaches to controlling Clostridioides difficile infection in healthcare settings
Abstract As today’s most prevalent and costly healthcare-associated infection, hospital-onset Clostridioides difficile infection (HO-CDI) represents a major threat to patient safety world-wide. This review will discuss how new insights into the epidemiology of CDI have quantified the prevalence of C...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-09-01
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| Series: | Antimicrobial Resistance and Infection Control |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13756-023-01295-z |
| _version_ | 1797556366724825088 |
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| author | Philip C. Carling Michael F. Parry Russell Olmstead |
| author_facet | Philip C. Carling Michael F. Parry Russell Olmstead |
| author_sort | Philip C. Carling |
| collection | DOAJ |
| description | Abstract As today’s most prevalent and costly healthcare-associated infection, hospital-onset Clostridioides difficile infection (HO-CDI) represents a major threat to patient safety world-wide. This review will discuss how new insights into the epidemiology of CDI have quantified the prevalence of C. difficile (CD) spore contamination of the patient-zone as well as the role of asymptomatically colonized patients who unavoidable contaminate their near and distant environments with resilient spores. Clarification of the epidemiology of CD in parallel with the development of a new generation of sporicidal agents which can be used on a daily basis without damaging surfaces, equipment, or the environment, led to the research discussed in this review. These advances underscore the potential for significantly mitigating HO-CDI when combined with ongoing programs for optimizing the thoroughness of cleaning as well as disinfection. The consequence of this paradigm-shift in environmental hygiene practice, particularly when combined with advances in hand hygiene practice, has the potential for significantly improving patient safety in hospitals globally by mitigating the acquisition of CD spores and, quite plausibly, other environmentally transmitted healthcare-associated pathogens. |
| first_indexed | 2024-03-10T17:00:45Z |
| format | Article |
| id | doaj.art-59ef69e71ca4456f98ef94205e411f94 |
| institution | Directory Open Access Journal |
| issn | 2047-2994 |
| language | English |
| last_indexed | 2024-03-10T17:00:45Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Antimicrobial Resistance and Infection Control |
| spelling | doaj.art-59ef69e71ca4456f98ef94205e411f942023-11-20T10:57:44ZengBMCAntimicrobial Resistance and Infection Control2047-29942023-09-0112111410.1186/s13756-023-01295-zEnvironmental approaches to controlling Clostridioides difficile infection in healthcare settingsPhilip C. Carling0Michael F. Parry1Russell Olmstead2Carney HospitalStamford Medical CenterTrinity HealthAbstract As today’s most prevalent and costly healthcare-associated infection, hospital-onset Clostridioides difficile infection (HO-CDI) represents a major threat to patient safety world-wide. This review will discuss how new insights into the epidemiology of CDI have quantified the prevalence of C. difficile (CD) spore contamination of the patient-zone as well as the role of asymptomatically colonized patients who unavoidable contaminate their near and distant environments with resilient spores. Clarification of the epidemiology of CD in parallel with the development of a new generation of sporicidal agents which can be used on a daily basis without damaging surfaces, equipment, or the environment, led to the research discussed in this review. These advances underscore the potential for significantly mitigating HO-CDI when combined with ongoing programs for optimizing the thoroughness of cleaning as well as disinfection. The consequence of this paradigm-shift in environmental hygiene practice, particularly when combined with advances in hand hygiene practice, has the potential for significantly improving patient safety in hospitals globally by mitigating the acquisition of CD spores and, quite plausibly, other environmentally transmitted healthcare-associated pathogens.https://doi.org/10.1186/s13756-023-01295-zClostridioides difficileHospital onset Clostridioides difficile infection preventionDisinfection cleaningOptimized cleaning performanceSporicidal disinfectantHealthcare-associated infections |
| spellingShingle | Philip C. Carling Michael F. Parry Russell Olmstead Environmental approaches to controlling Clostridioides difficile infection in healthcare settings Antimicrobial Resistance and Infection Control Clostridioides difficile Hospital onset Clostridioides difficile infection prevention Disinfection cleaning Optimized cleaning performance Sporicidal disinfectant Healthcare-associated infections |
| title | Environmental approaches to controlling Clostridioides difficile infection in healthcare settings |
| title_full | Environmental approaches to controlling Clostridioides difficile infection in healthcare settings |
| title_fullStr | Environmental approaches to controlling Clostridioides difficile infection in healthcare settings |
| title_full_unstemmed | Environmental approaches to controlling Clostridioides difficile infection in healthcare settings |
| title_short | Environmental approaches to controlling Clostridioides difficile infection in healthcare settings |
| title_sort | environmental approaches to controlling clostridioides difficile infection in healthcare settings |
| topic | Clostridioides difficile Hospital onset Clostridioides difficile infection prevention Disinfection cleaning Optimized cleaning performance Sporicidal disinfectant Healthcare-associated infections |
| url | https://doi.org/10.1186/s13756-023-01295-z |
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