Fungal periprosthetic joint infection of the hip: a systematic review

Periprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty with an incidence of approximately 1%. Due to the high risk of persisting infection, successful treatment of fungal PJI is challenging. The purpose of this study was to gain insight into the current management...

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Main Authors: Benjamin Schoof, Oliver Jakobs, Stefan Schmidl, Till Orla Klatte, Lars Frommelt, Thorsten Gehrke, Matthias Gebauer
Format: Article
Language:English
Published: Open Medical Publishing 2015-03-01
Series:Orthopedic Reviews
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/or/article/view/5748
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author Benjamin Schoof
Oliver Jakobs
Stefan Schmidl
Till Orla Klatte
Lars Frommelt
Thorsten Gehrke
Matthias Gebauer
author_facet Benjamin Schoof
Oliver Jakobs
Stefan Schmidl
Till Orla Klatte
Lars Frommelt
Thorsten Gehrke
Matthias Gebauer
author_sort Benjamin Schoof
collection DOAJ
description Periprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty with an incidence of approximately 1%. Due to the high risk of persisting infection, successful treatment of fungal PJI is challenging. The purpose of this study was to gain insight into the current management of fungal PJI of the hip and, by systematically reviewing the cases published so far, to further improve the medical treatment of this serious complication of total hip arthroplasty. Thus, we conducted a systematic review of the available literature concerning fungal PJI in total hip arthroplasty, including 45 cases of fungal PJI. At the moment a two-stage revision procedure is favorable and there is an ongoing discussion on the therapeutic effect of antifungal drug loaded cement spacers on fungal periprosthetic infections of the hip. Due to the fact that there is rare experience with it, there is urgent need to establish guidelines for the treatment of fungal infections of total hip arthroplasty.
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spelling doaj.art-59efc67e80814087823296d0395215572022-12-21T18:47:49ZengOpen Medical PublishingOrthopedic Reviews2035-82372035-81642015-03-017110.4081/or.2015.57483058Fungal periprosthetic joint infection of the hip: a systematic reviewBenjamin Schoof0Oliver Jakobs1Stefan Schmidl2Till Orla Klatte3Lars Frommelt4Thorsten Gehrke5Matthias Gebauer6Department of Orthopedic Surgery, HELIOS Endo-Clinic HamburgDepartment of Orthopedic Surgery, HELIOS Endo-Clinic HamburgDepartment of Orthopedic Surgery, HELIOS Endo-Clinic HamburgDepartment of Trauma-, Hand- and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, HamburgCentre of Infections and Microbiology, HELIOS Endo-Clinic, HamburgDepartment of Orthopedic Surgery, HELIOS Endo-Clinic HamburgDepartment of Orthopedic Surgery, HELIOS Endo-Clinic HamburgPeriprosthetic joint infection (PJI) is a severe complication of total joint arthroplasty with an incidence of approximately 1%. Due to the high risk of persisting infection, successful treatment of fungal PJI is challenging. The purpose of this study was to gain insight into the current management of fungal PJI of the hip and, by systematically reviewing the cases published so far, to further improve the medical treatment of this serious complication of total hip arthroplasty. Thus, we conducted a systematic review of the available literature concerning fungal PJI in total hip arthroplasty, including 45 cases of fungal PJI. At the moment a two-stage revision procedure is favorable and there is an ongoing discussion on the therapeutic effect of antifungal drug loaded cement spacers on fungal periprosthetic infections of the hip. Due to the fact that there is rare experience with it, there is urgent need to establish guidelines for the treatment of fungal infections of total hip arthroplasty.http://www.pagepress.org/journals/index.php/or/article/view/5748joint surgery, total hip arthroplasty, fungal periprosthetic infection
spellingShingle Benjamin Schoof
Oliver Jakobs
Stefan Schmidl
Till Orla Klatte
Lars Frommelt
Thorsten Gehrke
Matthias Gebauer
Fungal periprosthetic joint infection of the hip: a systematic review
Orthopedic Reviews
joint surgery, total hip arthroplasty, fungal periprosthetic infection
title Fungal periprosthetic joint infection of the hip: a systematic review
title_full Fungal periprosthetic joint infection of the hip: a systematic review
title_fullStr Fungal periprosthetic joint infection of the hip: a systematic review
title_full_unstemmed Fungal periprosthetic joint infection of the hip: a systematic review
title_short Fungal periprosthetic joint infection of the hip: a systematic review
title_sort fungal periprosthetic joint infection of the hip a systematic review
topic joint surgery, total hip arthroplasty, fungal periprosthetic infection
url http://www.pagepress.org/journals/index.php/or/article/view/5748
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