Aged Mice Devoid of the M<sub>3</sub> Muscarinic Acetylcholine Receptor Develop Mild Dry Eye Disease

Aged Mice Devoid of the M<sub>3</sub> Muscarinic Acetylcholine Receptor Develop Mild Dry Eye Disease

The parasympathetic nervous system is critically involved in the regulation of tear secretion by activating muscarinic acetylcholine receptors. Hence, various animal models targeting parasympathetic signaling have been developed to induce dry eye disease (DED). However, the muscarinic receptor subty...

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Bibliographic Details
Main Authors: Aytan Musayeva, Subao Jiang, Yue Ruan, Jenia Kouchek Zadeh, Panagiotis Chronopoulos, Norbert Pfeiffer, Werner E.G. Müller, Maximilian Ackermann, Ning Xia, Huige Li, Adrian Gericke
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
cornea
dry eye disease
M<sub>3</sub>
muscarinic receptor
tear secretion
Online Access:https://www.mdpi.com/1422-0067/22/11/6133

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