Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements

Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements

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Although homologous recombination between transposable elements can drive genomic evolution in yeast by facilitating chromosomal rearrangements, the details of the underlying mechanisms are not fully clarified. In the genome of the yeast Saccharomyces cerevisiae, the most common class of transposon...

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Bibliographic Details
Main Authors: Lei Qi, Yang Sui, Xing-Xing Tang, Ryan J. McGinty, Xiao-Zhuan Liang, Margaret Dominska, Ke Zhang, Sergei M. Mirkin, Dao-Qiong Zheng, Thomas D. Petes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879454/?tool=EBI

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