Cognitive impairments in young people with opioid addiction and their correction

Objective: to evaluate cognitive functions and drug correction of identified impairments in heroin users. Patients and methods. Thirty-two patients (7 women and 25 men) aged 18 to 45 years who had used heroin for 1—3 years were examined using the mini-mental state examination (MMSE), the techniques...

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Main Author: Maria Lazarevna Chukhlovina
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2012-09-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/142
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author Maria Lazarevna Chukhlovina
author_facet Maria Lazarevna Chukhlovina
author_sort Maria Lazarevna Chukhlovina
collection DOAJ
description Objective: to evaluate cognitive functions and drug correction of identified impairments in heroin users. Patients and methods. Thirty-two patients (7 women and 25 men) aged 18 to 45 years who had used heroin for 1—3 years were examined using the mini-mental state examination (MMSE), the techniques of «memorizing words» and «excluding words», the tests of «information-memory-concentration», quantitative assessment of clock drawing, and the frontal assessment battery. The detected cognitive impairments were corrected with the standardized Ginkgo Biloba extract (EGb 761 ®, Tanakan ®). Results. Cognitive impairments were found in all the patients: moderate cognitive disorders in 68.8% and mild dementia in 31.2%; thinking disorders were most noticeable; decreased attention, frontal lobe dysfunction, and visual spatial impairments were detectable. After a course of therapy with tanakan (120—240 g/day according to the degree of cognitive impairments for 3 months), there was a significant improvement in MMSE scores, thought, concentration, memory; however, they failed to achieve the scores in the control group consisting of 10 apparently healthy individuals of the same age and sex.
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spelling doaj.art-59f2cae143ce42149b0f0f9de18598262023-03-13T08:42:12ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422012-09-0143454710.14412/2074-2711-2012-402142Cognitive impairments in young people with opioid addiction and their correctionMaria Lazarevna ChukhlovinaObjective: to evaluate cognitive functions and drug correction of identified impairments in heroin users. Patients and methods. Thirty-two patients (7 women and 25 men) aged 18 to 45 years who had used heroin for 1—3 years were examined using the mini-mental state examination (MMSE), the techniques of «memorizing words» and «excluding words», the tests of «information-memory-concentration», quantitative assessment of clock drawing, and the frontal assessment battery. The detected cognitive impairments were corrected with the standardized Ginkgo Biloba extract (EGb 761 ®, Tanakan ®). Results. Cognitive impairments were found in all the patients: moderate cognitive disorders in 68.8% and mild dementia in 31.2%; thinking disorders were most noticeable; decreased attention, frontal lobe dysfunction, and visual spatial impairments were detectable. After a course of therapy with tanakan (120—240 g/day according to the degree of cognitive impairments for 3 months), there was a significant improvement in MMSE scores, thought, concentration, memory; however, they failed to achieve the scores in the control group consisting of 10 apparently healthy individuals of the same age and sex.https://nnp.ima-press.net/nnp/article/view/142cognitive functionsopioidsheroinginkgo biloba extract (egb 761tanakan )
spellingShingle Maria Lazarevna Chukhlovina
Cognitive impairments in young people with opioid addiction and their correction
Неврология, нейропсихиатрия, психосоматика
cognitive functions
opioids
heroin
ginkgo biloba extract (egb 761
tanakan )
title Cognitive impairments in young people with opioid addiction and their correction
title_full Cognitive impairments in young people with opioid addiction and their correction
title_fullStr Cognitive impairments in young people with opioid addiction and their correction
title_full_unstemmed Cognitive impairments in young people with opioid addiction and their correction
title_short Cognitive impairments in young people with opioid addiction and their correction
title_sort cognitive impairments in young people with opioid addiction and their correction
topic cognitive functions
opioids
heroin
ginkgo biloba extract (egb 761
tanakan )
url https://nnp.ima-press.net/nnp/article/view/142
work_keys_str_mv AT marialazarevnachukhlovina cognitiveimpairmentsinyoungpeoplewithopioidaddictionandtheircorrection