Cognitive impairments in young people with opioid addiction and their correction
Objective: to evaluate cognitive functions and drug correction of identified impairments in heroin users. Patients and methods. Thirty-two patients (7 women and 25 men) aged 18 to 45 years who had used heroin for 1—3 years were examined using the mini-mental state examination (MMSE), the techniques...
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Format: | Article |
Language: | Russian |
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IMA-PRESS LLC
2012-09-01
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Series: | Неврология, нейропсихиатрия, психосоматика |
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Online Access: | https://nnp.ima-press.net/nnp/article/view/142 |
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author | Maria Lazarevna Chukhlovina |
author_facet | Maria Lazarevna Chukhlovina |
author_sort | Maria Lazarevna Chukhlovina |
collection | DOAJ |
description | Objective: to evaluate cognitive functions and drug correction of identified impairments in heroin users. Patients and methods. Thirty-two patients (7 women and 25 men) aged 18 to 45 years who had used heroin for 1—3 years were examined using the mini-mental state examination (MMSE), the techniques of «memorizing words» and «excluding words», the tests of «information-memory-concentration», quantitative assessment of clock drawing, and the frontal assessment battery. The detected cognitive impairments were corrected with the standardized Ginkgo Biloba extract (EGb 761 ®, Tanakan ®). Results. Cognitive impairments were found in all the patients: moderate cognitive disorders in 68.8% and mild dementia in 31.2%; thinking disorders were most noticeable; decreased attention, frontal lobe dysfunction, and visual spatial impairments were detectable. After a course of therapy with tanakan (120—240 g/day according to the degree of cognitive impairments for 3 months), there was a significant improvement in MMSE scores, thought, concentration, memory; however, they failed to achieve the scores in the control group consisting of 10 apparently healthy individuals of the same age and sex. |
first_indexed | 2024-04-10T02:04:01Z |
format | Article |
id | doaj.art-59f2cae143ce42149b0f0f9de1859826 |
institution | Directory Open Access Journal |
issn | 2074-2711 2310-1342 |
language | Russian |
last_indexed | 2024-04-10T02:04:01Z |
publishDate | 2012-09-01 |
publisher | IMA-PRESS LLC |
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series | Неврология, нейропсихиатрия, психосоматика |
spelling | doaj.art-59f2cae143ce42149b0f0f9de18598262023-03-13T08:42:12ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422012-09-0143454710.14412/2074-2711-2012-402142Cognitive impairments in young people with opioid addiction and their correctionMaria Lazarevna ChukhlovinaObjective: to evaluate cognitive functions and drug correction of identified impairments in heroin users. Patients and methods. Thirty-two patients (7 women and 25 men) aged 18 to 45 years who had used heroin for 1—3 years were examined using the mini-mental state examination (MMSE), the techniques of «memorizing words» and «excluding words», the tests of «information-memory-concentration», quantitative assessment of clock drawing, and the frontal assessment battery. The detected cognitive impairments were corrected with the standardized Ginkgo Biloba extract (EGb 761 ®, Tanakan ®). Results. Cognitive impairments were found in all the patients: moderate cognitive disorders in 68.8% and mild dementia in 31.2%; thinking disorders were most noticeable; decreased attention, frontal lobe dysfunction, and visual spatial impairments were detectable. After a course of therapy with tanakan (120—240 g/day according to the degree of cognitive impairments for 3 months), there was a significant improvement in MMSE scores, thought, concentration, memory; however, they failed to achieve the scores in the control group consisting of 10 apparently healthy individuals of the same age and sex.https://nnp.ima-press.net/nnp/article/view/142cognitive functionsopioidsheroinginkgo biloba extract (egb 761tanakan ) |
spellingShingle | Maria Lazarevna Chukhlovina Cognitive impairments in young people with opioid addiction and their correction Неврология, нейропсихиатрия, психосоматика cognitive functions opioids heroin ginkgo biloba extract (egb 761 tanakan ) |
title | Cognitive impairments in young people with opioid addiction and their correction |
title_full | Cognitive impairments in young people with opioid addiction and their correction |
title_fullStr | Cognitive impairments in young people with opioid addiction and their correction |
title_full_unstemmed | Cognitive impairments in young people with opioid addiction and their correction |
title_short | Cognitive impairments in young people with opioid addiction and their correction |
title_sort | cognitive impairments in young people with opioid addiction and their correction |
topic | cognitive functions opioids heroin ginkgo biloba extract (egb 761 tanakan ) |
url | https://nnp.ima-press.net/nnp/article/view/142 |
work_keys_str_mv | AT marialazarevnachukhlovina cognitiveimpairmentsinyoungpeoplewithopioidaddictionandtheircorrection |