Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital

Background The long-term outcomes of patients discharged from the hospital after successful care in intensive care unit (ICU) are not briskly evaluated in Korea. The aim of this study was to assess long-term mortality of patients treated in the ICU and discharged alive from the hospital and to ident...

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Main Authors: Se Hee Na, Cheung Soo Shin, Gwan Ho Kim, Jae Hoon Kim, Jong Seok Lee
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2020-04-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kja-d-18-00275.pdf
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author Se Hee Na
Cheung Soo Shin
Gwan Ho Kim
Jae Hoon Kim
Jong Seok Lee
author_facet Se Hee Na
Cheung Soo Shin
Gwan Ho Kim
Jae Hoon Kim
Jong Seok Lee
author_sort Se Hee Na
collection DOAJ
description Background The long-term outcomes of patients discharged from the hospital after successful care in intensive care unit (ICU) are not briskly evaluated in Korea. The aim of this study was to assess long-term mortality of patients treated in the ICU and discharged alive from the hospital and to identify predictive factors of mortality. Methods In 3,679 adult patients discharged alive from the hospital after ICU care between 2006 and 2011, the 1-year mortality rate (primary outcome measure) was investigated. Various factors were entered into multivariate analysis to identify independent factors of 1-year mortality, including sex, age, severity of illness (APACHE II score), mechanical ventilation, malignancy, readmission, type of admission (emergency, elective surgery, and medical), and diagnostic category (trauma and non-trauma). Results The 1-year mortality rate was 13.4%. Risk factors that were associated with 1-year mortality included age (hazard ratio: 1.03 [95% CI, 1.02–1.04], P < 0.001), APACHE II score (1.03 [1.01–1.04], P < 0.001), mechanical ventilation (1.96 [1.60–2.41], P < 0.001), malignancy (2.31 [1.82–2.94], P < 0.001), readmission (1.65 [1.31–2.07], P < 0.001), emergency surgery (1.66 [1.18–2.34], P = 0.003), ICU admission due to medical causes (4.66 [3.68–5.91], P < 0.001), and non-traumatic diagnostic category (6.04 [1.50–24.38], P = 0.012). Conclusions The 1-year mortality rate was 13.4%. Old age, high APACHE II score, mechanical ventilation, malignancy, readmission, emergency surgery, ICU admission due to medical causes, and non-traumatic diagnostic category except metabolic/endocrinologic category were associated with 1-year mortality.
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spelling doaj.art-59f4f8820a444c84bb104af4be3ca1782022-12-22T00:16:11ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632020-04-0173212913610.4097/kja.d.18.002758550Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospitalSe Hee Na0Cheung Soo Shin1Gwan Ho Kim2Jae Hoon Kim3Jong Seok Lee4 Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, KoreaBackground The long-term outcomes of patients discharged from the hospital after successful care in intensive care unit (ICU) are not briskly evaluated in Korea. The aim of this study was to assess long-term mortality of patients treated in the ICU and discharged alive from the hospital and to identify predictive factors of mortality. Methods In 3,679 adult patients discharged alive from the hospital after ICU care between 2006 and 2011, the 1-year mortality rate (primary outcome measure) was investigated. Various factors were entered into multivariate analysis to identify independent factors of 1-year mortality, including sex, age, severity of illness (APACHE II score), mechanical ventilation, malignancy, readmission, type of admission (emergency, elective surgery, and medical), and diagnostic category (trauma and non-trauma). Results The 1-year mortality rate was 13.4%. Risk factors that were associated with 1-year mortality included age (hazard ratio: 1.03 [95% CI, 1.02–1.04], P < 0.001), APACHE II score (1.03 [1.01–1.04], P < 0.001), mechanical ventilation (1.96 [1.60–2.41], P < 0.001), malignancy (2.31 [1.82–2.94], P < 0.001), readmission (1.65 [1.31–2.07], P < 0.001), emergency surgery (1.66 [1.18–2.34], P = 0.003), ICU admission due to medical causes (4.66 [3.68–5.91], P < 0.001), and non-traumatic diagnostic category (6.04 [1.50–24.38], P = 0.012). Conclusions The 1-year mortality rate was 13.4%. Old age, high APACHE II score, mechanical ventilation, malignancy, readmission, emergency surgery, ICU admission due to medical causes, and non-traumatic diagnostic category except metabolic/endocrinologic category were associated with 1-year mortality.http://ekja.org/upload/pdf/kja-d-18-00275.pdfcritical care outcomesintensive care unitlong-term outcomesmortalityrisk factorssurvival analysis
spellingShingle Se Hee Na
Cheung Soo Shin
Gwan Ho Kim
Jae Hoon Kim
Jong Seok Lee
Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital
Korean Journal of Anesthesiology
critical care outcomes
intensive care unit
long-term outcomes
mortality
risk factors
survival analysis
title Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital
title_full Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital
title_fullStr Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital
title_full_unstemmed Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital
title_short Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital
title_sort long term mortality of patients discharged from the hospital after successful critical care in the icu in korea a retrospective observational study in a single tertiary care teaching hospital
topic critical care outcomes
intensive care unit
long-term outcomes
mortality
risk factors
survival analysis
url http://ekja.org/upload/pdf/kja-d-18-00275.pdf
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