Bone Scan in Identification, Assessment of Initial Extent and Response to Therapy in Polymyositis

This is a 51-year-old male who presented with abdominal pain, bilateral proximal upper and lower extremities pain and weakness, and decreased urine output with abnormal kidney function test; Urea and creatinine levels were elevated at 231.5 mg/dl and 11.05 mg/dl, respectively. Initial bone scan show...

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Main Authors: Malik Juweid, Noor Mashhadani, Omar Albtoush, Rahma Doudeen, Ahmad Al-Momani, Mohammed Aloqaily, Akram Al-ibraheem
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-01-01
Series:Asia Oceania Journal of Nuclear Medicine and Biology
Subjects:
Online Access:https://aojnmb.mums.ac.ir/article_18855_d692aaae61cbe405e790a99f1d54eb8a.pdf
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author Malik Juweid
Noor Mashhadani
Omar Albtoush
Rahma Doudeen
Ahmad Al-Momani
Mohammed Aloqaily
Akram Al-ibraheem
author_facet Malik Juweid
Noor Mashhadani
Omar Albtoush
Rahma Doudeen
Ahmad Al-Momani
Mohammed Aloqaily
Akram Al-ibraheem
author_sort Malik Juweid
collection DOAJ
description This is a 51-year-old male who presented with abdominal pain, bilateral proximal upper and lower extremities pain and weakness, and decreased urine output with abnormal kidney function test; Urea and creatinine levels were elevated at 231.5 mg/dl and 11.05 mg/dl, respectively. Initial bone scan showed increased uptake within several muscles suspicious for polymyositis, this was confirmed by biopsy of the right triceps, identified by bone scan as the best superficial biopsy site. Pelvis and thigh MRI demonstrated diffuse hyperintense signal on fluid sensitive sequences involving several muscles. Renal biopsy showed acute tubular injury. He was treated with steroids resulting in significant improvement. A repeat bone scan showed near complete resolution of the muscular uptake seen at presentation. This case nicely illustrates the role of bone scanning in the initial recognition and determination of the extent of polymyositis with identification of a suitable biopsy site as well as assessment of response to treatment.
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spelling doaj.art-59f63dc01a684c41a55423c225cafade2022-12-21T21:21:26ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262022-01-01101646710.22038/aojnmb.2021.57818.140318855Bone Scan in Identification, Assessment of Initial Extent and Response to Therapy in PolymyositisMalik Juweid0Noor Mashhadani1Omar Albtoush2Rahma Doudeen3Ahmad Al-Momani4Mohammed Aloqaily5Akram Al-ibraheem6Department of Radiology and Nuclear Medicine, School of Medicine, University of Jordan, Amman, JordanDepartment of Radiology and Nuclear Medicine, School of Medicine, University of Jordan, Amman, JordanDepartment of Radiology and Nuclear Medicine, School of Medicine, University of Jordan, Amman, JordanDepartment of Radiology and Nuclear Medicine, School of Medicine, University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanDepartment of Nuclear Medicine, King Hussein Cancer Center, Amman, JordanThis is a 51-year-old male who presented with abdominal pain, bilateral proximal upper and lower extremities pain and weakness, and decreased urine output with abnormal kidney function test; Urea and creatinine levels were elevated at 231.5 mg/dl and 11.05 mg/dl, respectively. Initial bone scan showed increased uptake within several muscles suspicious for polymyositis, this was confirmed by biopsy of the right triceps, identified by bone scan as the best superficial biopsy site. Pelvis and thigh MRI demonstrated diffuse hyperintense signal on fluid sensitive sequences involving several muscles. Renal biopsy showed acute tubular injury. He was treated with steroids resulting in significant improvement. A repeat bone scan showed near complete resolution of the muscular uptake seen at presentation. This case nicely illustrates the role of bone scanning in the initial recognition and determination of the extent of polymyositis with identification of a suitable biopsy site as well as assessment of response to treatment.https://aojnmb.mums.ac.ir/article_18855_d692aaae61cbe405e790a99f1d54eb8a.pdfpolymyositisbone scanmri
spellingShingle Malik Juweid
Noor Mashhadani
Omar Albtoush
Rahma Doudeen
Ahmad Al-Momani
Mohammed Aloqaily
Akram Al-ibraheem
Bone Scan in Identification, Assessment of Initial Extent and Response to Therapy in Polymyositis
Asia Oceania Journal of Nuclear Medicine and Biology
polymyositis
bone scan
mri
title Bone Scan in Identification, Assessment of Initial Extent and Response to Therapy in Polymyositis
title_full Bone Scan in Identification, Assessment of Initial Extent and Response to Therapy in Polymyositis
title_fullStr Bone Scan in Identification, Assessment of Initial Extent and Response to Therapy in Polymyositis
title_full_unstemmed Bone Scan in Identification, Assessment of Initial Extent and Response to Therapy in Polymyositis
title_short Bone Scan in Identification, Assessment of Initial Extent and Response to Therapy in Polymyositis
title_sort bone scan in identification assessment of initial extent and response to therapy in polymyositis
topic polymyositis
bone scan
mri
url https://aojnmb.mums.ac.ir/article_18855_d692aaae61cbe405e790a99f1d54eb8a.pdf
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